ID   A0A2K5DUQ8_AOTNA        Unreviewed;       812 AA.
AC   A0A2K5DUQ8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Ras interacting protein 1 {ECO:0000313|Ensembl:ENSANAP00000024637.1};
GN   Name=RASIP1 {ECO:0000313|Ensembl:ENSANAP00000024637.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000024637.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000024637.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5DUQ8; -.
DR   STRING; 37293.ENSANAP00000024637; -.
DR   Ensembl; ENSANAT00000042556.1; ENSANAP00000024637.1; ENSANAG00000030043.1.
DR   GeneTree; ENSGT00940000160072; -.
DR   OMA; WKPKTGC; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0051020; F:GTPase binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl.
DR   GO; GO:1905709; P:negative regulation of membrane permeability; IEA:Ensembl.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0033625; P:positive regulation of integrin activation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   CDD; cd15472; Myo5p-like_CBD_Rasip1; 1.
DR   InterPro; IPR037983; CBD_Rasip1/Radil.
DR   InterPro; IPR002710; Dilute_dom.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR16027; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR   PANTHER; PTHR16027:SF4; RAS-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF01843; DIL; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM01132; DIL; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51126; DILUTE; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          144..251
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          485..746
FT                   /note="Dilute"
FT                   /evidence="ECO:0000259|PROSITE:PS51126"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          35..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..258
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   812 AA;  86946 MW;  FD59A439C5242F71 CRC64;
     MLSGERKEGG SPRFGKLHLP VGLWINSPRK QLAKLGRRWP SAASVKSSSS DTGSRSSEPI
     PPPPPHVELR RVGAVKAAGG ASGSRAKRIS QLFRGSGTGT TGSGGAGGPG TPGGAQRWAS
     EKKLPELAAG VAPEPPLVTR ATAPPGVLKI FGAGLASGAN YKSVLATARS TARELVAEAL
     ERYGLAGSPG GGPGESSCVD AFALCDALAG RRGGRGEPSG GRAPARAGDS EQLWRARPAG
     QRRFELRGRE EARRLEQDLR GTGAPSWRPQ KNRSRAASGG AALASPGPGT GSGAPAGSGG
     KERSENLSLR RSVSELSLQG RRRRQQERRQ QALSMAPGAA DVQIGPADPG DFDQLTQCLI
     QAPSNRPYFL LLQGYQDAQV SAAPAPHAQS PRSHLRDGVS PCWPGWGGEE ALLGEIPARD
     LPPLGPATLL ALCVQHSARE LELGHLPRLL GRLARLIKEA VWVSAPIAVQ PRHHPEGVPE
     VPLTPEVVSV ELRPLMLWMA NTTELLSFVQ EKVLEMEKEA DQEDPQLCND LELCDEAMAL
     LDEVIMCTFQ QSVYYLTKTL YSTLPALLDS NPFTAGAELP GPGAELGAMP PGLRPTLSVF
     QAALELTNQC ELHPDLVSQT FGYLFFFSNA SLLNSLMERG QGRPFYQWSR AVQIRTNLDL
     VLDWLQGAGL GDIATEFFRK LSMAVNLLCV PRTSLLKASW SSLRTEHPTL TPAQLHHLLS
     HYQLGPGRGP PSAWDPAPAE RESVDTGDIF ESFSSHPPLI LPLGSSRLSL NGPVTDDALH
     RELRRLRRLL WDLEQQELPA NYRHGPPVAP PP
//