ID   A0A2K5DZB6_AOTNA        Unreviewed;       306 AA.
AC   A0A2K5DZB6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Divergent protein kinase domain 1A {ECO:0000313|Ensembl:ENSANAP00000026336.1};
GN   Name=DIPK1A {ECO:0000313|Ensembl:ENSANAP00000026336.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000026336.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000026336.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004648}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the DIPK family.
CC       {ECO:0000256|ARBA:ARBA00006338}.
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DR   AlphaFoldDB; A0A2K5DZB6; -.
DR   Ensembl; ENSANAT00000044261.1; ENSANAP00000026336.1; ENSANAG00000030882.1.
DR   GeneTree; ENSGT00390000006452; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022049; FAM69_kinase_dom.
DR   InterPro; IPR029244; FAM69_N.
DR   PANTHER; PTHR21093:SF4; DIVERGENT PROTEIN KINASE DOMAIN 1A; 1.
DR   PANTHER; PTHR21093; UNCHARACTERIZED; 1.
DR   Pfam; PF12260; PIP49_C; 1.
DR   Pfam; PF14875; PIP49_N; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          1..50
FT                   /note="FAM69 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14875"
FT   DOMAIN          72..273
FT                   /note="FAM69 protein-kinase"
FT                   /evidence="ECO:0000259|Pfam:PF12260"
SQ   SEQUENCE   306 AA;  34495 MW;  41C343F1F06D2D9D CRC64;
     CDKYKTGVID GPACNSLCVT ETLYFGKCLS TKPNNQAKLG DQGNLSELVN LILTVADGDK
     DGQVSLGEAK SAWALLQLNE FLLMVILQDK EHTPKLMGFC GDLYVMESVE YTSLYGISLP
     WVIELFIPSG FRRSMDQLFT PSWPRKAKIA IGLLEFVEDV FHGPYGNFLM CDTSAKNLGY
     NDKYDLKMVD MRKIVPETNL KELIKDRHCE SDLDCVYGTD CRTSCDQSTM KCTSEVIQPN
     LAKACQLLKD YLLRGAPSEI REELEKQLYS CIALKVTANQ MEMEHSLILN NLKTLLWKKI
     SYTNDS
//