ID   A0A2K5E2C0_AOTNA        Unreviewed;       340 AA.
AC   A0A2K5E2C0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=HSF-type DNA-binding domain-containing protein {ECO:0000259|SMART:SM00415};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000027288.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000027288.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC       ECO:0000256|RuleBase:RU004020}.
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DR   AlphaFoldDB; A0A2K5E2C0; -.
DR   STRING; 37293.ENSANAP00000027288; -.
DR   Ensembl; ENSANAT00000045289.1; ENSANAP00000027288.1; ENSANAG00000031481.1.
DR   GeneTree; ENSGT00940000161825; -.
DR   OMA; SATAWME; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR   PANTHER; PTHR10015:SF140; HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED MEMBER 3-RELATED; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          79..182
FT                   /note="HSF-type DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM00415"
FT   REGION          1..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          222..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..243
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   340 AA;  37780 MW;  8591BBA89FBE87F4 CRC64;
     MASQNTEQEY EAKLAPSVGG EPTSGGPSSS SPDPNVDSRE LLDRHEDQAV SQDSGSQDNP
     QPEDQNQRVA SMEDNRNLFR LSFPRKLWMM VEEDTFQSVN WNDDGDAVII EKDLLQREIL
     QRRGAEKIFK TDSLKSFIRQ LNLYGFRKIR ASTSPRDKNV MIYHNSNFQR GKPWLLENIR
     RNGDLRNATQ QATHVPAPKR SKLVPIRHPL QIHHSNDKDA AIEMSQGGTP NVQGPSGTQS
     FPCPHPGTWP IYVNPITGHP PGYGPPQEPN DPNREGTSGN DAFASSATAG MESAREVPSS
     LVCPDISSLM FSCNVCYSIL LASLLVMTPN EPSDDEEEEE
//