ID   A0A2K5E2Z3_AOTNA        Unreviewed;       669 AA.
AC   A0A2K5E2Z3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=FERM domain containing kindlin 2 {ECO:0000313|Ensembl:ENSANAP00000027524.1};
GN   Name=FERMT2 {ECO:0000313|Ensembl:ENSANAP00000027524.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000027524.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000027524.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5E2Z3; -.
DR   Ensembl; ENSANAT00000045534.1; ENSANAP00000027524.1; ENSANAG00000031245.1.
DR   GeneTree; ENSGT00390000013444; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd13205; FERM_C_fermitin; 1.
DR   CDD; cd17181; FERM_F0_KIND2; 1.
DR   CDD; cd17184; FERM_F1_KIND2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR037843; Kindlin/fermitin.
DR   InterPro; IPR040790; Kindlin_2_N.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR16160; FERMITIN 2-RELATED; 1.
DR   PANTHER; PTHR16160:SF11; FERMITIN FAMILY HOMOLOG 2; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF18124; Kindlin_2_N; 1.
DR   SMART; SM00295; B41; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47031; Second domain of FERM; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          93..562
FT                   /note="Band 4.1"
FT                   /evidence="ECO:0000259|SMART:SM00295"
FT   REGION          141..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  76551 MW;  DE6C0354A1E253EB CRC64;
     MALDGIRMPD GCYADGTWEL SVHVTDLNRD VTLRVTGEVH IGGVMLKLVE KLDVKKDWSD
     HALWWEKKRT WLLKTHWTLD KYGIQADAKL QFTPQHKLLR LQLPNMKYVK VKVNFSDRVF
     KAVSDICKTF NIRHPEELSL LKKPRDPTKK KKKKLDDQSE DEALELEGPL ITPGSGSIYS
     SPGLYSKTMT PTYDAHDGSP LSPTSAWFGD SALSEGNPGI LAVSQPITSP EILAKMFKPQ
     ALLDKAKINQ GWLDSSRSLM EQDVKENEAL LLRFKYYSFF DLNPKYDAIR INQLYEQAKW
     AILLEEIECT EEEMMMFAAL QYHINKLSIM TSENHLNNSD KDVDEVDAAL SDLEITLEGG
     KTSTILGDIT SIPELADYIK AKKADSERLQ AVLVHLQRHI HFFGTPAHQM NLRGCEVTPD
     VNISGQKFNI KLLIPVAEGM NEIWLRCDNE KQYAHWMAAC RLASKGKTMA DSSYNLEVQN
     ILSFLKMQHL NPDPQLIPEQ ITTDINPECL VSPRYLKKYK NKQITARILE AHQNVAQMSL
     IEAKMRFIQA WQSLPEFGIT HFIARFQGGK KEELIGIAYN RLIRMDASTG DAIKTWRFSN
     MKQWNVNWEI KMVTVEFADE VRLSFICTEV DCKVVHEFIG GYIFLSTRAK DQNESLDEEM
     FYKLTSGWV
//