ID A0A2K5E320_AOTNA Unreviewed; 469 AA.
AC A0A2K5E320;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Keratin 72 {ECO:0000313|Ensembl:ENSANAP00000027645.1};
GN Name=KRT72 {ECO:0000313|Ensembl:ENSANAP00000027645.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000027645.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000027645.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_012305685.1; XM_012450262.1.
DR AlphaFoldDB; A0A2K5E320; -.
DR Ensembl; ENSANAT00000045659.1; ENSANAP00000027645.1; ENSANAG00000031663.1.
DR GeneID; 105715836; -.
DR CTD; 140807; -.
DR GeneTree; ENSGT00940000162105; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF2; KERATIN, TYPE II CYTOSKELETAL 72; 1.
DR Pfam; PF00038; Filament; 2.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 125..396
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 444..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 180..256
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 315..374
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 469 AA; 50985 MW; CED8D818066F479E CRC64;
MSRQLTHFPG GERLGFSGCS AVLSGRIGSS STSFRAGVKG SASFGSKSLF CLGGSRRLAL
SAAAGRGGGR LGGFVGTVFG SAGLGPACPS VCPPGGIPQV TVNKSLLAPL NVELDSEIQK
VRAQEREQIK ALNNKFASFI DKVRFLEQQN QVLETKWELL QQLDLNNCRN NLEPILEGYI
SNLRKQLETL SGDRVRLDSE LRNMQDLVED YKKRYEVEIN RRTAAENEFV VLKKDVDAAY
MNKVELQAKV DSLTDEIKFF KCLYEGEIAQ IQSHISDTSV ILSMDNNRDL DLDSIIAEVR
AQYEEIALKS KAEAEALYQT KCANLETAIA DAEQRGDCAL KDARAKLDEL EGALHQAKEE
LARMLREYQE LMSLKLALDV EIATYRKLLE SEECRMSGEY PNSVSISVIS STNAGAGGAG
FSMGFGASSS YSYKTAAADV KTKGSCGSEL KDPLAKTSGG SCATRKASR
//
