ID   A0A2K5E4Q8_AOTNA        Unreviewed;       937 AA.
AC   A0A2K5E4Q8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Family with sequence similarity 13 member B {ECO:0000313|Ensembl:ENSANAP00000028240.1};
GN   Name=FAM13B {ECO:0000313|Ensembl:ENSANAP00000028240.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000028240.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000028240.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAM13 family.
CC       {ECO:0000256|ARBA:ARBA00007549}.
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DR   RefSeq; XP_012289921.1; XM_012434498.1.
DR   RefSeq; XP_012290004.1; XM_012434581.1.
DR   AlphaFoldDB; A0A2K5E4Q8; -.
DR   STRING; 37293.ENSANAP00000028240; -.
DR   Ensembl; ENSANAT00000046264.1; ENSANAP00000028240.1; ENSANAG00000031888.1.
DR   GeneID; 105704965; -.
DR   CTD; 51306; -.
DR   GeneTree; ENSGT00950000183033; -.
DR   OMA; SSITEQX; -.
DR   OrthoDB; 1333388at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04393; RhoGAP_FAM13A1a; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR039102; FAM13.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR15904; FAM13; 1.
DR   PANTHER; PTHR15904:SF16; PROTEIN FAM13B; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          23..212
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          508..543
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          643..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        655..670
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   937 AA;  107203 MW;  2322450E1EC9BAF3 CRC64;
     MRKSSSPSLS NCNSVLANKI FGIPLDELQQ GGHPDNEVPF IVRHVVDYIE EHGGLEQQGL
     FQVNGNAETV EWLRQRYDSG EEVDLVKEAD VPSAISLLRF FLQELPEPVI PDSLHIHLMQ
     LSQDYNNEDE FGRKLRFLLQ QLPPVNYSLL KFLCRFLANV ASHHEEIWSA DSLAAVFGPD
     VFHIYTDVED MKEQEIVSRI MAGLLENYYE FFENEEEDFS SNDLSSITEQ VNELSEEEED
     EKLEHIEELP EEGAEKSNDM PEVVQLRMTE NILESNSVTA STSTHISPIS ILPASTDILE
     RTIRAAVEQH LFDLQSSIDH DLKNLQQQNV VCNNEAESIH CDGEGSDNQV NIADDIINAS
     ESNRDCSEPV ASTNLDNEVM QQDCVFENEE NNQSVGILLE PCSDHGDSED GCPEREEYLL
     FDSDKLSHLI LDSSSKICDL NANTESEVPG GQSVGVQGEA ACVHIPHLDL KNVSDGDKWE
     ASCLITFPLI DFKTMHLQRD GEEPFPAFKS WQEDSESGEA QLSPQAGRMN HHPLEEDCPP
     VLSHRSLDFG QSQRFLHDPE KLDSSSKALS FTRIRRSSFS SKEEKREDRT PYQLVKKLQK
     KIRQFEEQFE RERNSKPSYS DIAANPKVLK WMTELTKLRK QIKDAKHKSS DGEFVPQTRP
     RSNTLPKSFG SSLDHEDEEN EDEPKVIQKE KKPTKEATLE LILKRLKEKR IERCLPEDIK
     KMTKDHLVEE KASLQKSLLY YESQHGRPVT REERHIVKPL YDRYRLVKQM LTRASITPIL
     GSPSTKRRGQ MLQPIIEGET AHFFEEIKEE EEDGVNLSSE LSDILKTAVQ IQSSLENSES
     DVDENQEKLA LDLRLSSSRA ASMPELLEQL WKARAEKKKL RKTLREFEEA FYQQNGRNAQ
     KEDRVPVLEE YREYKKIKAK LRLLEVLISK QDSSKSI
//