ID   A0A2K5E5V8_AOTNA        Unreviewed;       563 AA.
AC   A0A2K5E5V8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=PX domain containing serine/threonine kinase like {ECO:0000313|Ensembl:ENSANAP00000028538.1};
GN   Name=PXK {ECO:0000313|Ensembl:ENSANAP00000028538.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000028538.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000028538.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5E5V8; -.
DR   Ensembl; ENSANAT00000046564.1; ENSANAP00000028538.1; ENSANAG00000031813.1.
DR   GeneTree; ENSGT00390000017669; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   PANTHER; PTHR22999:SF40; PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN; 1.
DR   PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS50195; PX; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          1..109
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   DOMAIN          71..464
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          420..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        420..443
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..491
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   563 AA;  63697 MW;  8C4FC3A1BA330615 CRC64;
     MAFMEKPPAG KVLLDDTVPL TAAIEASQSL QSHTIVRRYS DFDLLNNSLQ IAGLSLPLPP
     KKLIGNMDRE FIAERQKGLQ NYLNVITTNH ILSNCELVKK FLDPNNYSAN YTEIALQQVS
     MFFRSEPKWE VVEPLKDIGW RIRKKYFLMK IKNQPKERLV LNWADLGPDK YLSDKDFQCL
     IKLLPSCLHP YIYRVTFATA NESSALLIRM FNEKGTLKDL IYKAKPKDPF LKKYCNPKKI
     QGLELQQIKT YGRQILEVLK FLHDKGFPYG HLHASNVMLD GDTCRLLDLE NSLLGLPSFY
     RSYFSQFRKI NTLESVDVHC FGHLLYEMTY GRPPDSVPVD SFPPAPSMAV VAVLESTLSC
     EACKNGMPTV SRLLQMPLFS DVLLTTSEKP QFKIPTKLKE ALRIAKECIE KRLIEEQKQI
     HQHRRLTRAQ SHHGSEEERK KRKILARKKS KRSALESSEE HSAKYNNSNN SGSGASSPLT
     SPSSPTPPST SAALGLGKRC KDRDICITST SSTSTTTSSS LASCEHRGTC PALAPGCEWC
     EPRGLAQLHP EFPKRNFEES RNL
//