ID A0A2K5E5X0_AOTNA Unreviewed; 539 AA.
AC A0A2K5E5X0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Glycerophosphodiester phosphodiesterase domain containing 2 {ECO:0000313|Ensembl:ENSANAP00000028591.1};
GN Name=GDPD2 {ECO:0000313|Ensembl:ENSANAP00000028591.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000028591.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000028591.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000256|ARBA:ARBA00007277}.
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DR RefSeq; XP_012330477.1; XM_012475054.1.
DR AlphaFoldDB; A0A2K5E5X0; -.
DR Ensembl; ENSANAT00000046618.1; ENSANAP00000028591.1; ENSANAG00000032100.1.
DR GeneID; 105732810; -.
DR CTD; 54857; -.
DR GeneTree; ENSGT00940000159625; -.
DR OrthoDB; 203377at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR23344:SF1; GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE GDPD2; 1.
DR PANTHER; PTHR23344; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR Pfam; PF13653; GDPD_2; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 224..479
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 539 AA; 61796 MW; AD7ED78603CB5945 CRC64;
MAESLGCCSV WARCLHCLYS CHWRKCPRER MQTSKCDCIW FGLLILTFLL SLSWLYIGLV
LLNDLHNFNE FLFRHWGHWM DWSLAFLLVI SLLVTYASLL LVLALLLQLC RQPLHLHSLH
KVLLLLIMLL VAAGLVGLDI QWQQEWHSLR VSLQATAPFL HVGAVAGITL LAWPVADTFY
RIHRRGLKIL LLLLFFGFVL VIYLAPLCIS SPCIMEPRDL PPKPGLVGHR GAPMLAPENT
MMSLRKTAEC GATVFETDVM ISSDGIPFLM HDEHLSRTTN VASVFPTRIT AHSSDFSWAE
LKRLNAGAWF LERRPFWGAK PLAGPDQKEA ESQTVPALEE LLEEAAALNL SIMFDLRRPP
QNHTYYDTFV IQTLETVLNA RVPQAMVFWL PDEDRANVQR RAPGMRQIYG RQGGNRTERP
QFLNLPYQDL PLLDIKALHK DNVSVNLFVV NKPWLFSLLW CAGVDSVTTN DCQLLQQMRY
PIWLITPQNY LIMWAITNCV STMLLLWIFL LRRRFGKKRE KTGLKTAVLL TRINNFLTE
//
