ID A0A2K5E9N7_AOTNA Unreviewed; 681 AA.
AC A0A2K5E9N7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SET and MYND domain-containing protein 4 {ECO:0000256|ARBA:ARBA00026173};
GN Name=SMYD4 {ECO:0000313|Ensembl:ENSANAP00000029884.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000029884.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000029884.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A2K5E9N7; -.
DR STRING; 37293.ENSANAP00000029884; -.
DR Ensembl; ENSANAT00000047914.1; ENSANAP00000029884.1; ENSANAG00000032713.1.
DR GeneTree; ENSGT00730000111079; -.
DR OMA; FDCTCPA; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007507; P:heart development; IEA:Ensembl.
DR CDD; cd10536; SET_SMYD4; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044421; SMYD4_SET.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR46165; SET AND MYND DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46165:SF2; SET AND MYND DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 140..452
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 203..242
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
SQ SEQUENCE 681 AA; 75124 MW; C4649FF95AFC8E70 CRC64;
GVSHSRPNTE DMSLCYANRS AALFHLGQYE MCLKDIIRAQ THGYPERLQP KVMLRKAECL
VALGRLQEAH QTISDLERNF TASPTLADFP SQSVQKNLHH LKMKVQEKEN LTETFPAALA
KTLEGVDLRE ENKQLSNASS SVSLCMDPLK GRCLVATREI LPGELLVKED AFVSVLNPGE
LPPLHHSLDS KWDTRVTIGD LYCHRCLKHT LATVPCDGCS YAKYCSQECL QQAWELYHRI
ECPLGGLLLT LGVFCHTALR LTLLVGFEDV SKIRKLYDEV SNKDICLPES SSWVKTLNSG
LGEIEKNGKI IETPIPGCDV NGKYESNYQA VFNLLPHTEN HTPRDIKSSC TLQLEAASFQ
TVTTGANSSQ LKAATAAPVL THLSFPLALS GSKEGIVTSS RQVRLATGIF PVVSLLNHSC
SPNTSVSFIS TVATIRASQR IGKGQEILHC YGPHKNRMGV AERQQKLRSQ YFFDCTCPAC
HTEAHRMATR PRWEAFCCNS CRAPMQGDDV LSCGHRGCAV SVRRDHLASR LQDLRQQVGM
ARKLLSDGKL EPAIQQLSGC QRDAESFLSA EHAVLGEIED GLAQACAALG DWQKSATHLQ
NSLRVVEARH GPSSVEMGRE LFKLAQIFFN GFAVPEALST IRKAEEVLSL HCGPWDDEIQ
ELQKMKSCLL DLTPTPVGPS V
//
