ID   A0A2K5EFK9_AOTNA        Unreviewed;       481 AA.
AC   A0A2K5EFK9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Catenin alpha-1 {ECO:0008006|Google:ProtNLM};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000031949.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000031949.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC       {ECO:0000256|ARBA:ARBA00004536}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the vinculin/alpha-catenin family.
CC       {ECO:0000256|ARBA:ARBA00008376}.
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DR   AlphaFoldDB; A0A2K5EFK9; -.
DR   Ensembl; ENSANAT00000049996.1; ENSANAP00000031949.1; ENSANAG00000033636.1.
DR   GeneTree; ENSGT01030000234543; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0015629; C:actin cytoskeleton; IEA:InterPro.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.250.2510; -; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 3.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR001033; Alpha_catenin.
DR   InterPro; IPR006077; Vinculin/catenin.
DR   InterPro; IPR000633; Vinculin_CS.
DR   PANTHER; PTHR18914; ALPHA CATENIN; 1.
DR   PANTHER; PTHR18914:SF24; CATENIN ALPHA-1; 1.
DR   Pfam; PF01044; Vinculin; 1.
DR   PRINTS; PR00805; ALPHACATENIN.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 2.
DR   PROSITE; PS00663; VINCULIN_1; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
SQ   SEQUENCE   481 AA;  53075 MW;  DBC472262221B901 CRC64;
     MTAVHAGNIN VNLEIRTLAV ERLLKTLVTH ATTLVNTNSR SKKAHVLAAS VDQATENFLD
     KGDKIAESQF LKEELVAAVE DVQKQGDLMK TAAGEFADDP CSSVKRGNMI RAARALLSAV
     TQLLILADMA DLKVVEDGIL KLRNAGNEQD LGIQYKTLKP EVDKLDIMAA KRQQELKDVG
     HRDQMAAARG ILQKNVPILY TASQACLQHS DVTAYKANRD QIYKQLQQVV TGISNAAQAT
     ASDDASQHQW GGGGELAYAL NNFEKQITVD PLSFSEECFR PSLEERLESI ISRVALMADS
     SCTRDDCHER IVAECNAVRQ ALQDLLSEYM GNAGHKERSD ELSSAIDKMT KKTRDLYRQL
     RKAIMDHVSD SFLETNVPLL VSIEAAKNGN EKEVKEYAQV FRGQANKLIE VANLACSISN
     NKEGVKLVRM SASQLEVINA ALALAAKPQS KLAQENMDLF KEQWEKQVCV LTDAGITFWK
     M
//