ID A0A2K5EG14_AOTNA Unreviewed; 342 AA.
AC A0A2K5EG14;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Aquaporin 7 {ECO:0008006|Google:ProtNLM};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000032152.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000032152.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
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DR RefSeq; XP_012318622.1; XM_012463199.1.
DR AlphaFoldDB; A0A2K5EG14; -.
DR STRING; 37293.ENSANAP00000032152; -.
DR Ensembl; ENSANAT00000050201.1; ENSANAP00000032152.1; ENSANAG00000033778.1.
DR GeneID; 105724536; -.
DR CTD; 364; -.
DR GeneTree; ENSGT00940000159054; -.
DR OMA; AYKPHYD; -.
DR OrthoDB; 5490746at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005811; C:lipid droplet; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0015250; F:water channel activity; IEA:UniProt.
DR GO; GO:0015793; P:glycerol transmembrane transport; IEA:Ensembl.
DR GO; GO:0070295; P:renal water absorption; IEA:Ensembl.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR NCBIfam; TIGR00861; MIP; 1.
DR PANTHER; PTHR43829; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR43829:SF15; AQUAPORIN-7; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR02019; AQUAPORIN7.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 37..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 304..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 37439 MW; 5F74CA980959BB0C CRC64;
MIHTSKHRRS TRSSKMVSWS GITRIQQILQ KKLVREFLAE FMSTYVMMVF GLGSVAHMVL
SKKHGSYLAV NLAFGFGVTM GVHVAGNISG AHMNAAVTFA NCALGRLPWR KFPVYVLGQC
LGSFLAAATI YTLFYTAILH FSGGQLMVTG PVATAGIFAT YLPEYMTLWR GFLNEMWLTG
MLQLCLFAIT DQENNPALPG TQALVIGILV VTIGMSLGMN TGYAINPSRD LPPRIFTFIA
GWGKQVFSDG ENWWWVPVVA PPLGAYLGGI IYVVFIGSTI PREPPKLEDS VVYEDHRITV
SSKMEPHASV ASPLTPVSVS PDNRPSVHPA PTLQESVAQE HF
//
