ID   A0A2K5EGC7_AOTNA        Unreviewed;       577 AA.
AC   A0A2K5EGC7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN   Name=SLCO3A1 {ECO:0000313|Ensembl:ENSANAP00000032296.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000032296.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000032296.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC       {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR   AlphaFoldDB; A0A2K5EGC7; -.
DR   Ensembl; ENSANAT00000050346.1; ENSANAP00000032296.1; ENSANAG00000033843.1.
DR   GeneTree; ENSGT01080000257410; -.
DR   OMA; NINCECQ; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR002350; Kazal_dom.
DR   InterPro; IPR036058; Kazal_dom_sf.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004156; OATP.
DR   NCBIfam; TIGR00805; oat; 1.
DR   PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR   PANTHER; PTHR11388:SF86; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1; 1.
DR   Pfam; PF07648; Kazal_2; 1.
DR   Pfam; PF03137; OATP; 1.
DR   SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS51465; KAZAL_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|RuleBase:RU362056};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362056};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT   TRANSMEM        60..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        98..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        146..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        307..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        459..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   TRANSMEM        510..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362056"
FT   DOMAIN          350..398
FT                   /note="Kazal-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51465"
FT   REGION          552..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  62220 MW;  BF0A816E9A60B436 CRC64;
     MALGALLSAL PEFLTHQYKY EAGEIRWGAE GRDVCAANGS GGDEGPDPDL ICRNRTATNM
     MYLLLIGAQV LLGIGATPVQ PLGVSYIDDH VRRKDSSLYI GILFTMLVFG PACGFILGSF
     CTKIYVDAVF IDTSNLDITP DDPRWIGAWW GGFLLCGALL FFSSLLMFGF PQSLPPHSDP
     AMESQQAMLP EREYERPKPS NGVLRHPLEP DSSASCFQQL RVIPKVTKHL LSNPVFTCII
     LAACMEIAVV AGFAAFLGKY LEQQFNLTTS SANQLLGMTA IPCACLGIFL GGLLVKKLSL
     SALGAIRMAM LVNLVSTACY VSFLFLGCDT GPVAGVTVPY GNNTAPGSAL DPYSPCNNNC
     ECQTDSFTPV CGADGITYLS ACFAGCNSTN LTGCACLTTV PAENATVVPG KCPSPGCQEA
     FLTFLCVMCI CSLIGAMAQT PSVIILIRTV SPELKSYALG VLFLLLRLLG FIPPPLIFGA
     GIDSTCLFWS TFCGEQGACV LYDNVVYRYL YVSIAIALKS FAFILYTTTW QCLRKNYKRY
     IKNHEGGLST STEYQDIETE KTCPESHSPS EDSFVRS
//