ID   A0A2K5EHG9_AOTNA        Unreviewed;       142 AA.
AC   A0A2K5EHG9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Glycine cleavage system H protein, mitochondrial {ECO:0000256|ARBA:ARBA00018130};
DE   AltName: Full=Lipoic acid-containing protein {ECO:0000256|ARBA:ARBA00033419};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000032629.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000032629.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GcvH family.
CC       {ECO:0000256|ARBA:ARBA00009249}.
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DR   AlphaFoldDB; A0A2K5EHG9; -.
DR   STRING; 37293.ENSANAP00000032629; -.
DR   Ensembl; ENSANAT00000050683.1; ENSANAP00000032629.1; ENSANAG00000034008.1.
DR   GeneTree; ENSGT00390000011666; -.
DR   OMA; WIAQIKL; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005960; C:glycine cleavage complex; IEA:InterPro.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProt.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:InterPro.
DR   CDD; cd06848; GCS_H; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR002930; GCV_H.
DR   InterPro; IPR033753; GCV_H/Fam206.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR11715; GLYCINE CLEAVAGE SYSTEM H PROTEIN; 1.
DR   PANTHER; PTHR11715:SF43; GLYCINE CLEAVAGE SYSTEM H PROTEIN, MITOCHONDRIAL; 1.
DR   Pfam; PF01597; GCV_H; 1.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
PE   3: Inferred from homology;
KW   Lipoyl {ECO:0000256|ARBA:ARBA00022823};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..142
FT                   /note="Glycine cleavage system H protein, mitochondrial"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014363604"
FT   DOMAIN          61..142
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50968"
SQ   SEQUENCE   142 AA;  15071 MW;  10EAF198A574DF1F CRC64;
     MAIMRAVLCS LCAVPAPAAP CLLRAWQLGA GVIRTLCTGL ALLSVCKFIE KHEWITTENG
     IGTVGISNFA QEALGDVVYC SLLEVGTKLN KQDEFGALES VKAASELYSP LSGEVPEINE
     ALAENPGLVN KFYYEDGCGS CL
//