ID A0A2K5EIC5_AOTNA Unreviewed; 757 AA.
AC A0A2K5EIC5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=CD248 molecule {ECO:0000313|Ensembl:ENSANAP00000032977.1};
GN Name=CD248 {ECO:0000313|Ensembl:ENSANAP00000032977.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000032977.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000032977.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5EIC5; -.
DR STRING; 37293.ENSANAP00000032977; -.
DR Ensembl; ENSANAT00000051031.1; ENSANAP00000032977.1; ENSANAG00000034174.1.
DR GeneTree; ENSGT00940000162405; -.
DR OMA; APNKRIT; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR GO; GO:0072577; P:endothelial cell apoptotic process; IEA:Ensembl.
DR GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR GO; GO:0048144; P:fibroblast proliferation; IEA:Ensembl.
DR GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IEA:Ensembl.
DR GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR CDD; cd03600; CLECT_thrombomodulin_like; 1.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR14789; CHONDROLECTIN VARIANT CHODLFDELTAE; 1.
DR PANTHER; PTHR14789:SF4; ENDOSIALIN; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..757
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014386379"
FT TRANSMEM 686..711
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..147
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 409..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 80636 MW; 113F89315AC6C351 CRC64;
MLLRLLLAWA AAGPTLGQDS RTPEPRAACG PGSCYALFPK RRTFLEAWRA CRELGGNLAT
PRTPEEARRV DSLVGAGPAS RLLWIGLQRQ ARQCQPQRPL RGFTWTTGDQ DTAFTNWAQP
ATGGPCPAQR CVALEAGGEH RWLEGSCTLA VDGYLCQFGF EGACPALQEE AGQAGPAVYT
TPFHLVSTEF EWLPFGSVAA VQCQAGRGAS LLCVKQPEGG VGWSRAGPLC PGTGCGPDNG
GCEHECVEEV DGHVSCRCTE GFRLAADGQS CEDPCAQAPC EQQCEPGGAQ GYSCHCRLGF
RPAEDDPHRC VDTDECQIAG VCQQMCVNYV GGFECYCSEG HELEADGISC SPAGAIGARA
SPDLEDELLV DGEDEEDEDE AWEAIDGGWT EMPGILWMEP TQPPDFALAY RPSFPEDGDP
QKPHPEPTWP PPLSAPRVPY HSSVLSVTRP VVVSATRPTL PSAHQPPVIP ATHPDLPRDH
QIPVIAANYP DLPSAYQPGI LSVSHPARPP AHQPPMISTK YPELFPAHRS PMFPDTQVTG
TQTTTHLPGI PPNRAPLITT LGAHQPPLAP DVPILRTQAT QLPIIPTAQA SVTTASRSPV
SPAHQVSVPA ATQPPAPPTL LASQSPTNQT LPISPTHPHS KAPQIPREGG PHPKLAPWLP
SAAPTAAPTA LGEAGLTGHS QRDDRWLLVA LLVPTCVFLV VLLALGIVYC TRCGPHAPNK
RITDCYRWVT HAGSKSPTEP MPPRGSLTGV QTCRTSV
//
