ID A0A2K5EJU7_AOTNA Unreviewed; 544 AA.
AC A0A2K5EJU7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Zinc finger protein 34 {ECO:0008006|Google:ProtNLM};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000033482.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000033482.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012328700.1; XM_012473277.1.
DR RefSeq; XP_012328701.1; XM_012473278.1.
DR AlphaFoldDB; A0A2K5EJU7; -.
DR Ensembl; ENSANAT00000051540.1; ENSANAP00000033482.1; ENSANAG00000034412.1.
DR GeneID; 105731499; -.
DR CTD; 80778; -.
DR GeneTree; ENSGT00940000153104; -.
DR OrthoDB; 5247610at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47772:SF4; REDUCED EXPRESSION 2-RELATED; 1.
DR PANTHER; PTHR47772; ZINC FINGER PROTEIN 200; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..87
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 180..207
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 235..262
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 263..290
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 291..318
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 319..346
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 347..374
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 375..402
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 403..430
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 431..458
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 459..486
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 487..514
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 515..542
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 122..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 62300 MW; 05B8849EC59E83F9 CRC64;
MAALFLSAPP QAEVTFEDVA VLLSREEWGR LGPAQRGLYR DVMLETYGNL VSLGVGPAGP
KPGVISQLER GDEPWVLDVQ GTSGREYLRV NSPALGTSTE YKELTSRETF DEEELGRLRG
IFPQGSEPVD ASNHAGKPEG SLEKLVEQSR PVTLTKGESS RESGESLRLV SRPVPDQRPH
KCDICEQSFE QRSYLNNHKR VHRSKKTNTI RDSGEIFNAN FVKEDQKIPT GKKLHYCSYC
GKTFRYSANL VKHQRLHSEE KPYKCDECGK AFSQSCEFIN HRRMHSGEIP YRCDECGKTF
NRRPNLMKHQ RIHTGEKPYK CGECGKHFSA YSSLIYHQRI HTGEKPYKCN DCGKAFSDGS
ILIRHRRTHT GEKPFECKEC GKGFTQSSNL IQHQRIHTGE KPYKCNECEK AFIQKTKLVE
HQRSHTGEKP YECNDCGKVF SQSTHLIQHQ RIHTGEKPYK CSECGKAFHN SSRLIHHQRS
HHGEKPYKCS DCKKAFSQST YLIQHRRIHT GEKPYKCSEC GKAFRHSSNM CQHQRIHLRE
DFSV
//
