ID A0A2K5ELN8_AOTNA Unreviewed; 758 AA.
AC A0A2K5ELN8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Splicing factor Cactin {ECO:0000256|ARBA:ARBA00034534};
GN Name=CACTIN {ECO:0000313|Ensembl:ENSANAP00000034128.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000034128.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000034128.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CACTIN family.
CC {ECO:0000256|ARBA:ARBA00006895}.
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DR AlphaFoldDB; A0A2K5ELN8; -.
DR Ensembl; ENSANAT00000052190.1; ENSANAP00000034128.1; ENSANAG00000034680.1.
DR GeneTree; ENSGT00950000183102; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019134; Cactin_C.
DR InterPro; IPR018816; Cactin_central.
DR PANTHER; PTHR21737:SF6; CACTIN; 1.
DR PANTHER; PTHR21737; POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3; 1.
DR Pfam; PF10312; Cactin_mid; 1.
DR Pfam; PF09732; CactinC_cactus; 1.
DR SMART; SM01050; CactinC_cactus; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 271..458
FT /note="Splicing factor cactin central"
FT /evidence="ECO:0000259|Pfam:PF10312"
FT DOMAIN 634..758
FT /note="Splicing factor Cactin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09732"
FT REGION 1..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 227..272
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 25..53
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..540
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 88677 MW; 91826F2510C12A30 CRC64;
MGRDTRSRSR SAGRRGQRQR SQSGSRSRSR SHGRRNRRRR EDEGRHRRRR RSRERRSDSE
EERWQRSGMR SQSPSKSRWR SRDGSSQSDS GEEPSRDQWS RRRRRRARSW SPGSSASSSA
SPGRSQSPRA AAAALSQQQS LQERLRLREE RKQQEELMKA FETPEEKRAR RLAKKEAKER
KKREKMGWGE EYMGYTNTDN PFGDNNLLGT FIWNKALEKK GISHLEEKEL KERNKRIQED
NRLELQKVKQ LRLEREREKA MREQELEMLQ REKEAEHFKT WEEQEDNFHL QQAKLRSKIR
IRDGRAKPID LLAKYISAED DDLAVEMHEP YTFLNGLTVA DMEDLLEDIQ VYMELEQGKN
ADFWRDMTTI TEDEISKLRK LEASGKGPGE RREGVNASVS SDVQSVFKGK TYTQLQVIFQ
GIEGKIRTGG PNLDMGYWES LLQQLRAHMA RARLRERHQD VLRQKLYKLK QEQGVESEPL
FPILKQEPQS PGRSLESEDA APTPPGPSSE GGPTEAEVDG SAPTEGDGDG DGDGDGDGDV
LMEEDLIQQS LDDYDAGRYS PRLLTAHELP LDAHVLEPDE DLQRLQLSRQ QLQVTGDASE
SAEDIFFRRA KEGMGQDEAQ FSVEMPLTGK AYLWADKYRP RKPRFFNRVH TGFEWNKYNQ
THYDFDNPPP KIVQGYKFNI FYPDLIDKRS TPEYFLEACS DNKDFAILRF HAGPPYEDIA
FKIVNREWEY SHRHGFRCQF ANGIFQLWFH FKRYRYRR
//
