ID A0A2K5ENX1_AOTNA Unreviewed; 830 AA.
AC A0A2K5ENX1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=DENN domain containing 1A {ECO:0000313|Ensembl:ENSANAP00000034901.1};
GN Name=DENND1A {ECO:0000313|Ensembl:ENSANAP00000034901.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000034901.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000034901.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K5ENX1; -.
DR Ensembl; ENSANAT00000052967.1; ENSANAP00000034901.1; ENSANAG00000034989.1.
DR GeneTree; ENSGT00940000156261; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 6.10.140.1000; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR040032; DENND1A/B/C.
DR InterPro; IPR037516; Tripartite_DENN.
DR PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR13196:SF22; DENN DOMAIN-CONTAINING PROTEIN 1A; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 1..195
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 270..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 748..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..782
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 830 AA; 90183 MW; 44ADF9713E46AF0E CRC64;
MLHLYASMLY ERRILIICSK LSTLTACIHG SAAMLYPMYW QHVYIPVLPP HLLDYCCAPM
PYLIGIHLSL MEKVRNMALD DVVILNVDTN TLETPFDDLQ SLPNDVISSL KNRLKKVSTT
TGDGVARAFL KAQAAFFGSY RNALKIEPEE PITFCEEAFV SHYRSGAMRQ FLQNATQLQL
FKQFIDGRLD LLNSGEGFSD VFEEEINMGE YAGSDKLYHQ WLSTVRKGSG AILNTVKTKA
NPAMKTVYKF AKDHAKMGIK EVKNRLKQKD IAENGCAPTP EEQLPKTAPS PLVEAKDPKL
REDRRPITVH FGQVRPPRPH VVKRPKSNIT VEGRRTSVPS PEQPQPYRTL KESDSAEGDE
AESPEQRVRK PVGPVPAPPD RAASIDLLED VFSNLDMEAP LQPLGQAKSL EDLRAPKDLR
EQPGTFDYQR LDLGGSERSR GMAMALKLAH PYNKLWSLGQ DDMAIPSKPP AASPEKPLAL
LGNSLALPRR PQNQDSILNP SDKEEVPTPT LGSITIPRPQ GRKTPELGIV PPPPVARPAK
LQAAGTELGD FSEQLQTDRD RRAALSPALF PGLLPRVVPQ GPTELLQPLS PGPGAAGTSS
DALLALLDPL STAWSGSTLP PRHSAPNVAT PFTPQFSFPP VGTPTPFPQP PLNPFVPSMS
AAPHTLPLVS TPARPFGAPP ASLGPAFASG LLLSSAGFCA PHRSQPNLSA LSMPNLFGQV
PMGTHTSPLQ PLGPPAVAPS RIRTLPLARS SARAAEAKQG LALRPGDPQL LPPRPPQGLE
PALRPSAPQQ ARDPFEDLLL KTKQDVSPSP APAPAPGSVE QLRKQWETFE
//
