ID   A0A2K5EPE2_AOTNA        Unreviewed;       784 AA.
AC   A0A2K5EPE2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Semaphorin 3F {ECO:0000313|Ensembl:ENSANAP00000035076.1};
GN   Name=SEMA3F {ECO:0000313|Ensembl:ENSANAP00000035076.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000035076.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000035076.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the semaphorin family.
CC       {ECO:0000256|ARBA:ARBA00009492}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; A0A2K5EPE2; -.
DR   Ensembl; ENSANAT00000053143.1; ENSANAP00000035076.1; ENSANAG00000035038.1.
DR   GeneTree; ENSGT00940000156703; -.
DR   OMA; HQDYIFY; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR   GO; GO:0048731; P:system development; IEA:UniProt.
DR   CDD; cd05871; Ig_Sema3; 1.
DR   CDD; cd11254; Sema_3F; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF27; SEMAPHORIN-3F; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00408; IGc2; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..784
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014368631"
FT   DOMAIN          31..544
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   DOMAIN          618..694
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          752..784
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        768..784
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   784 AA;  88123 MW;  380EE3E0811CC65E CRC64;
     MLVAGLLLWA SLLTGAWPAF PTQDHLPATP RVRLSFKELK ATGTAHFFNF LLNTTDYRIL
     LKDEDHDRMY VGSKDYVLSL DLHDINREPL IIHWAASQQR IEECVLSGKD GNGECGNFVR
     LIQPWNRTHL YVCGTGAYNP MCTYVNRGRR AQATPWTQAQ VVRGRGSRAT DGALRPIPTA
     PRQDYIFYLE PERLESGKGK CPYDPKLDTA SALINEELYA GVYIDFMGTD AAIFRTLGKQ
     TAMRTDQYNS RWLNDPSFIH AELIPDSSER NDDKLYFFFR ERSAEAPQSP AVYARIGRIC
     LNDDGGHCCL VNKWSTFLKA RLVCSVPGED GIETHFDELQ DVFVQQTLDV RNPVIYAVFT
     SSGSVFRGSA VCVYSMADIR MVFNGPFAHK EGPNYQWMPF SGKMPYPRPG TCPGGTFTPS
     MKSTKDYPDE VINFMRSHPL MYQAVYPLQR RPLVVRTGAP YRLTTVAVDQ VDAADGRYEV
     LFLGTDRGTV QKVIVLPKDD QEMEELMLEE VEVFKVGVTI PSLTSPVLQQ LYVASAVGVT
     HLSLHRCQAY GAACADCCLA RDPYCAWDGQ ACSRYTASSK RRSRRQDVRH GNPIRQCRGF
     NSNANKNAVE SVQYGVAGSA AFLECQPRSP QATVKWLFQR DPGDRRREIR AEDRFLRTEQ
     GLLLRALQLS DRGLYSCTAT ENNFKHIVTR VQLHVLGRDA VHAALFPPLA VSAPPSPGAG
     PPTPPYQELA QLLAQPEVGL IHQYCQGYWR HVPPSPREAP GAPRPPEYQD QKKPRNRRHH
     PPDT
//