ID   A0A2K5ET83_AOTNA        Unreviewed;       475 AA.
AC   A0A2K5ET83;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Ataxin-10 {ECO:0000256|ARBA:ARBA00018804};
GN   Name=ATXN10 {ECO:0000313|Ensembl:ENSANAP00000036388.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000036388.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000036388.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Necessary for the survival of cerebellar neurons. Induces
CC       neuritogenesis by activating the Ras-MAP kinase pathway. May play a
CC       role in the maintenance of a critical intracellular glycosylation level
CC       and homeostasis. {ECO:0000256|ARBA:ARBA00002116}.
CC   -!- SIMILARITY: Belongs to the ataxin-10 family.
CC       {ECO:0000256|ARBA:ARBA00008384}.
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DR   RefSeq; XP_012304883.1; XM_012449460.1.
DR   AlphaFoldDB; A0A2K5ET83; -.
DR   STRING; 37293.ENSANAP00000036388; -.
DR   Ensembl; ENSANAT00000054459.1; ENSANAP00000036388.1; ENSANAG00000035670.1.
DR   GeneID; 105715199; -.
DR   CTD; 25814; -.
DR   GeneTree; ENSGT00390000010377; -.
DR   OMA; CAWESPP; -.
DR   OrthoDB; 5479391at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR   GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019156; Ataxin-10_domain.
DR   PANTHER; PTHR13255; ATAXIN-10; 1.
DR   PANTHER; PTHR13255:SF0; ATAXIN-10; 1.
DR   Pfam; PF09759; Atx10homo_assoc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          370..460
FT                   /note="Ataxin-10"
FT                   /evidence="ECO:0000259|Pfam:PF09759"
SQ   SEQUENCE   475 AA;  53481 MW;  AA14A34065417814 CRC64;
     MAAPRPPPAR LSGVMVPAPI QDLEALRALT ALFKEQRNRE TAPRTIFQRV LDILKKSSHA
     VELACRDPSQ AENLASSLQL ITECFRCLRN ACIECSVNQN SIRNLDTIGV AVDLILLFRE
     LRVEQESLLT AFRCGLQFLG NIASRNEDSQ SIVWVHAFPE LFLSCLNHPD KKIVAYSSMI
     LFTSLNHERM KELEENLNIA IDVIDAYQRH PESEWPFLII TDLFLKSSEL VQAMFPKLNN
     QERVTLLDLM IAKLTSEEPL TKDDIPVFLH HAELVSSTFV DQCKTVLRLA SEDPPDDEEA
     LATIRLLDVL CEMTANTELL GYLQVFPGLL ERVIDLLRVI HVAAKETTNI FSTCGCVRAE
     GDISNVAEGF KSHLIRLIGN LCYKNKDNQD KVNELDGIPL ILDNCSVSDS NPFLTQWVIY
     AIRNLTEDNS QNQDVIAKME EQGLADPSLL KQMGFEVEKK GEKLILKSTR DTPKP
//