ID   A0A2K5EWK2_AOTNA        Unreviewed;       655 AA.
AC   A0A2K5EWK2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Zinc finger protein 408 {ECO:0000313|Ensembl:ENSANAP00000037614.1};
GN   Name=ZNF408 {ECO:0000313|Ensembl:ENSANAP00000037614.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000037614.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000037614.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K5EWK2; -.
DR   Ensembl; ENSANAT00000055697.1; ENSANAP00000037614.1; ENSANAG00000036294.1.
DR   GeneTree; ENSGT00930000151062; -.
DR   OMA; HRPEAPC; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR24379:SF67; IP01257P-RELATED; 1.
DR   PANTHER; PTHR24379; KRAB AND ZINC FINGER DOMAIN-CONTAINING; 1.
DR   Pfam; PF00096; zf-C2H2; 8.
DR   SMART; SM00355; ZnF_C2H2; 10.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00042}.
FT   DOMAIN          288..315
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          316..343
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          344..371
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          372..394
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          403..430
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          431..458
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          459..486
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          486..513
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          514..541
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          542..569
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          136..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          560..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..235
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   655 AA;  72225 MW;  06A26161EBFEBDEC CRC64;
     NQRLLTFQKF HLKFVPGRFQ NLFVFFPPTR PLQTHLRRTF VGLFQNLSLG PWGDVHACEQ
     SSGWTSLVQQ GRLESEGNVA PVRISERLHL QVYQVVLPGF ELLLWPRPSS EDPSLAQPGL
     DRQAAVAVVT EVESAVQQEV ASPGENAAEP CTDPGSQSPP DNQAESVVSP GLQFPTQDQL
     SKDSQPLGPL LQDGNVDEEY PPQAQIPPEL QSNSATQQDP DGSEASFSSS ARGTQLHAYL
     AKKLPSPSDQ CPPRAKTPEP GAQQPGFPAL SRSPPCPAGS SPKQGRRYRC GECGKAFLQL
     CHLKKHAFVH TGHKPFLCTE CGKSYSSEES FKAHTLGHRG VRPFPCPQCD KAYGTRRDLK
     EHQVVHSGAR PFACDQCGKA FARRPSLRLH HKTHQVPAAP APCPCPVCGR PLANQGSLRN
     HMRLHTGEKP FLCPHCGRAF RQRGNLRGHL RLHTGERPYR CPHCADAFPQ LPELRRHLIS
     HTGEAHLCPV CGKALRDPHT LRAHERLHSG ERPFPCPQCG RAYTLATKLR RHLKSHLADK
     PYRCPTCGMG YTLLQSLRRH QLSHRPEAPS GPPSVPSAAS EPTVMLLQAE PQLMDTHREQ
     DVSPVRDVVE VTISESREKC FVVPEEPGAA PSLVLIHKDL GFSAWAEVVE VETGT
//