ID   A0A2K5F0B5_AOTNA        Unreviewed;       307 AA.
AC   A0A2K5F0B5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Ion channel TACAN {ECO:0000256|ARBA:ARBA00039635};
DE   AltName: Full=Transmembrane protein 120A {ECO:0000256|ARBA:ARBA00041456};
GN   Name=TMEM120A {ECO:0000313|Ensembl:ENSANAP00000038932.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000038932.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000038932.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Nucleus inner membrane
CC       {ECO:0000256|ARBA:ARBA00004473}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004473}.
CC   -!- SIMILARITY: Belongs to the TMEM120 family.
CC       {ECO:0000256|ARBA:ARBA00009700}.
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DR   AlphaFoldDB; A0A2K5F0B5; -.
DR   Ensembl; ENSANAT00000057028.1; ENSANAP00000038932.1; ENSANAG00000036879.1.
DR   GeneTree; ENSGT00390000007848; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012926; TACAN/TMEM120B.
DR   PANTHER; PTHR21433:SF1; ION CHANNEL TACAN; 1.
DR   PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR   Pfam; PF07851; TMPIT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   307 AA;  34493 MW;  86B9698828DA8680 CRC64;
     MQPPSPGPLG DCLRDWEDLQ QDFQNIQETH RLYRLKLEEL TKLQNNCTSS ITRQKKRLQE
     LAHTLKKCKP SLPAEAEEAA QELENQMKER QGLFFDMEAY LPKKNGLYLS LVLGNVNVTL
     LSKQAKFAYK DEYEKFKLYL TIILILISFT CRFLLNSRVT DAAFNFLLVW YYCTLTIRES
     ILINNGSRWA GRTPRLSPRG STEWGSGTLW EAGAGPGVGP SRGRNWDREG TDGVPKEIPE
     PVPVLFYVPE LRAVPPVLLP EWLPLPPAGA GRAAHHGPHC GGLPVLDVAG PHLPAAFSFL
     WTILAAF
//