ID A0A2K5F1Z6_AOTNA Unreviewed; 493 AA.
AC A0A2K5F1Z6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Butyrophilin subfamily 2 member A1 {ECO:0000313|Ensembl:ENSANAP00000039484.1};
GN Name=BTN2A1 {ECO:0000313|Ensembl:ENSANAP00000039484.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000039484.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000039484.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR AlphaFoldDB; A0A2K5F1Z6; -.
DR Ensembl; ENSANAT00000057585.1; ENSANAP00000039484.1; ENSANAG00000037121.1.
DR GeneTree; ENSGT00940000163835; -.
DR OMA; GHVAKPW; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd15819; SPRY_PRY_BTN1_2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR037958; SPRY/PRY_BTN1/2.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF148; BUTYROPHILIN SUBFAMILY 2 MEMBER A2; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022692};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..493
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014469773"
FT DOMAIN 12..139
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 269..462
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 493 AA; 55399 MW; F6097E51D693654E CRC64;
MEPAAALPFS LPASLLLPLL SLCALVSAQL TVVGPTDPIL AMVGENTTLR CHLSPEKNAE
DMEVRWFRSH FSPAVFVYKG GRQRTEEQME EYRGRTTFVS KDISRGSVAL VIHNVTAQEN
GTYRCYFQEG RSSDEAILRL VVAGLGSEPL VEMRGHEDGG ILLACISRGW YPKPLTVWRD
PFGEVVPSLK EDNTPDTDGL FMVTTAVIIR DRSVRHMSCS VNNTLLSQKK ESVIFIPDSS
SAWGILSTQM ESRKGEKKIL LGEKEFEREM REIAIKDLEK ERTSSAADVV LDPDTAHPEL
FLSEDRRSVR RGAFRQSVPD NPERFHSQPC VLSRESFTSG KHYWEVEVEN VLEWTVGVCR
DSVERKGEFL LLPQNGFWTL EMFGNQYRAL SSPERILPLK ESLCRLGVFL DYEAGDVSFY
NMRDRSHIYT CPRSVFSVPV RPFFRLGSYD SPIFICPALT GADGVTVPEE GLTLHRAGTH
HSPQDQFPGL TAM
//
