ID   A0A2K5F2K2_AOTNA        Unreviewed;       270 AA.
AC   A0A2K5F2K2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Ras association domain family member 1 {ECO:0000313|Ensembl:ENSANAP00000039653.1};
GN   Name=RASSF1 {ECO:0000313|Ensembl:ENSANAP00000039653.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000039653.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000039653.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_012323243.1; XM_012467820.1.
DR   AlphaFoldDB; A0A2K5F2K2; -.
DR   Ensembl; ENSANAT00000057754.1; ENSANAP00000039653.1; ENSANAG00000037201.1.
DR   GeneID; 105727729; -.
DR   CTD; 11186; -.
DR   GeneTree; ENSGT00940000155664; -.
DR   OMA; PAFEMTW; -.
DR   OrthoDB; 4260488at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd17218; RA_RASSF1; 1.
DR   CDD; cd21890; SARAH_RASSF1; 1.
DR   Gene3D; 1.20.5.110; -; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR033614; RASSF1-6.
DR   InterPro; IPR033600; RASSF1_RA.
DR   InterPro; IPR011524; SARAH_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR22738:SF12; RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22738; RASSF; 1.
DR   Pfam; PF16517; Nore1-SARAH; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50951; SARAH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          124..218
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          220..267
FT                   /note="SARAH"
FT                   /evidence="ECO:0000259|PROSITE:PS50951"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   270 AA;  31160 MW;  21D27F439E3A5EEC CRC64;
     MGEAETPSFE MTWSSTTSSG YCSQEDSDSE LEQYFTARTS LARRPRRDQD EPVEWETPDL
     SQAEIEKKIK EYNGQINSNL FMSLNKDGSY TGFIKVQLKL VRPVSVPSSK KPPSLQDARQ
     GPGRSASVRR RTSFYLPKDT VKHLHVLSRT RAREVIEALL RKFLVVDDPR KFALFERAER
     HGQVYLRKLS DDEQPLRLRL LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR
     EEEAHLRQIL QKYSYCRQKI QEALHACPLG
//