ID A0A2K5F8I6_AOTNA Unreviewed; 373 AA.
AC A0A2K5F8I6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Neuralized E3 ubiquitin protein ligase 1B {ECO:0000313|Ensembl:ENSANAP00000041781.1};
GN Name=NEURL1B {ECO:0000313|Ensembl:ENSANAP00000041781.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000041781.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000041781.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5F8I6; -.
DR Ensembl; ENSANAT00000059896.1; ENSANAP00000041781.1; ENSANAG00000038171.1.
DR GeneTree; ENSGT00940000157079; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16786; mRING-HC-C3HC5_NEU1B; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR037962; Neuralized.
DR InterPro; IPR006573; NHR_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12429:SF10; E3 UBIQUITIN-PROTEIN LIGASE NEURL1B; 1.
DR PANTHER; PTHR12429; NEURALIZED; 1.
DR Pfam; PF07177; Neuralized; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00588; NEUZ; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51065; NHR; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 97..251
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 321..361
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 254..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 38978 MW; 4A9B1F84A1E017E1 CRC64;
MGNTVHRTLP ESAFADTLTP ARLSQARFSA CLPPSSHDAA NFDNNELENN QVVAKLGHLA
LGRASGPPPA DAAAAAIPCG PRERPRPASS PALLEADLRF HATRGPDVSL SADRKIACAP
RPDGGRTLVF SERPLRPGES LFVEVGRPGL AAPGALAFGI TSCDPGGLRP NELPADPDAL
LDRKEYWVVA RAGPVPSGGD ALSFTLRPGG DVLLGVNGRP RGRLLCVDTT QALWAFFAVR
GGVAGQLRLL GTLQSSPATT TPSGSLSGSQ DDSDSDMTFS VNQSSSASES SLVTAPSSPL
SPPVSPAFSP PEPAGIKNGE CTVCFDGEVD TVIYTCGHMC LCHSCGLRLK RQARACCPIC
RRPIKDVIKI YRP
//
