ID A0A2K5F986_AOTNA Unreviewed; 1436 AA.
AC A0A2K5F986;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Talin 2 {ECO:0000313|Ensembl:ENSANAP00000042007.1};
GN Name=TLN2 {ECO:0000313|Ensembl:ENSANAP00000042007.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000042007.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000042007.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSANAT00000060123.1; ENSANAP00000042007.1; ENSANAG00000038172.1.
DR GeneTree; ENSGT00940000154699; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd12150; talin-RS; 1.
DR Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 2.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR Gene3D; 1.20.1420.10; Talin, central domain; 6.
DR InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR037438; Talin1/2-RS.
DR InterPro; IPR015009; Vinculin-bd_dom.
DR PANTHER; PTHR19981; TALIN; 1.
DR PANTHER; PTHR19981:SF34; TALIN-2; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR Pfam; PF08913; VBS; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF47220; alpha-catenin/vinculin-like; 5.
DR SUPFAM; SSF109885; I/LWEQ domain; 2.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 1188..1427
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT COILED 1395..1422
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1436 AA; 151137 MW; 0640928561A387EE CRC64;
QKRTSKWPLS ACKGVAARET AQALKTLAQA ARGVAASTTD PAAAHAMLDS ARDVMEGSAM
LIQEAKQALI APGDAESQQR LAQVAKAVSH SLNNCVNCLP GQKDVDVALK SIGESSKKLL
VDSLPPSTKP FQEAQSELNQ AAADLNQSAG EVVHATRGQS GELAAASGKF SDDFDEFLDA
GIEMAGQAQT KEDQIQVIGN LKNISMASSK LLLAAKSLSV DPGAPNAKNL LAAAARAVTE
SINQLITLCT QQAPGQKECD NALRELETVK GMLDNPNEPV SDLSYFDCIE SVMENSKVLG
ESMAGISQNA KTGDLPAFGE CVGIASKALC GLTEAAAQAA YLVGISDPNS QAGHQGLVDP
IQFARANQAI QMACQNLVDP GSSPSQVLSA ATIVAKHTSA LCNACRIASS KTANPVAKRH
FVQSAKEVAN STANLVKTIK ALDGDFSEDN RNKCRIATAP LIEAVENLTA FASNPEFVSI
PAQISSEGSQ AQEPILVSAK TMLESSSYLI RTARSLAINP KDPPTWSVLA GHSHTVSDSI
KSLITSIRDK APGQRECDYS IDGINRCIRD IEQASLAAVS QSLATRDDIS VEALQEQLTS
VVQEIGHLID PIATAARGEA AQLGHKVTQL ASYFEPLILA AVGVASKILD HQQQMTVLDQ
TKTLAESALQ MLYAAKEGGG NPKAQHTHDA ITEAAQLMKE AVDDIMVTLN EAASEVGLVG
GMVDAIAEAM SKLDEGTPPE PKGTFVDYQT TVVKYSKAIA VTAQEMMTKS VTNPEELGGL
ASQMTSDYGH LALQGQMAAA TAEPEEIGFQ IRTRVQDLGH GCIFLVQKAG ALQVCPTDSY
TKKELIECAR AVTEKVSLVL WALQAGNKGT QACITAATAV SGIIADLDTT IMFATAGTLN
AENSETFADH RENILKTAKA LVEDTKLLVS GAASTPDKLA QAAQSSAATI TQLAEVVKLG
AASLGSNDPE TQVVLINAIK DVAKALSDLI SATKGAASKP ADDPSMYQLK GAAKVMVTNV
TSLLKTVKAV EDEATRGTRA LEATIECIKQ ELTVFQSKDV PEKTSSPEES IRMTKGITMA
TAKAVAAGNS CRQEDVIATA NLSRKAVSDM LTACKQASFH PDVSDEVRTR ALRFGTECAL
GYLDLLEHVL VILQKPTPEL KQQLAAFSKR VAGAVTELIQ AAEAMKGTEW VDPEDPTVIA
ETELLGAAAS IEAAAKKLEQ LKPRAKPKQA DETLDFEEQI LEAAKSIAAA TSALVKSASA
AQRELVAQGK VGSIPANAAD DGQWSQGLIS AARMVAAATS SLCEAANASV QGHASEEKLI
SSAKQVAAST AQLLVACKVK ADQDSEAMRR LQAAGNAVKR ASDNLVRAAQ KAAFGKADDD
DVVVKTKFVG GIAQIIAAQE EMLKKERELE EARKKLAQIR QQQYKFLPTE LREDEG
//
