ID   A0A2K5H815_COLAP        Unreviewed;       848 AA.
AC   A0A2K5H815;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=B-cell receptor CD22 {ECO:0000256|ARBA:ARBA00040106};
DE   AltName: Full=Sialic acid-binding Ig-like lectin 2 {ECO:0000256|ARBA:ARBA00041781};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000000480.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000000480.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   RefSeq; XP_011803296.1; XM_011947906.1.
DR   AlphaFoldDB; A0A2K5H815; -.
DR   STRING; 336983.ENSCANP00000000480; -.
DR   Ensembl; ENSCANT00000001862.1; ENSCANP00000000480.1; ENSCANG00000001652.1.
DR   GeneID; 105515944; -.
DR   KEGG; cang:105515944; -.
DR   CTD; 933; -.
DR   OrthoDB; 4167621at2759; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd00096; Ig; 1.
DR   CDD; cd20938; IgC1_CD22_d2; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR46958; B-CELL RECEPTOR CD22; 1.
DR   PANTHER; PTHR46958:SF1; B-CELL RECEPTOR CD22; 1.
DR   Pfam; PF08205; C2-set_2; 1.
DR   Pfam; PF13895; Ig_2; 1.
DR   Pfam; PF13927; Ig_3; 3.
DR   SMART; SM00409; IG; 7.
DR   SMART; SM00408; IGc2; 4.
DR   SUPFAM; SSF48726; Immunoglobulin; 7.
DR   PROSITE; PS50835; IG_LIKE; 6.
PE   4: Predicted;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..848
FT                   /note="B-cell receptor CD22"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014386370"
FT   DOMAIN          144..236
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          243..327
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          332..417
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          420..501
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          506..583
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          594..677
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   848 AA;  95318 MW;  E3A6547F983CD4F7 CRC64;
     MHLLGPWLLL LVLEYLAFSD SSKWNIDHPE TLYAWEGACV WVPCTYRVLD GALESFILFH
     NPEYNKNISK FEGTRLYEST KDGKVPSGQK RVQFLGDKNN NNCTLSIHPV HVNDSGQLGL
     RMESKTEKWM EPIHLNVSER PFPPHIQLPP KLQESQEVSL TCSLNFSCYG YQIQLQWLLE
     GVPMRQAAVT LTSLSTKSVF TWSELKFSPQ WSHHGKTVTC ELHDVDGKVL SEDTVQLNVK
     HTPKLEIEVI PSEAIVREGD SVTVTCKVNS SNPEYTTVSW LKDDTPLKEQ NTLTLTLHKV
     TKSQSGRYCC RVSNDVGPGT SEKVFLQVQY APEPSRVQIV QSPAVEGNEV KFICTSPANP
     LPTNYTWYHN GKEVQGRTEK EFQIPKILPW HAGTYSCVAE NILGTGQRGP GAELDVQYPP
     KKVTMVIENP TPIREGDTVT LSCNYNSSNP IVNHYEWKPR GAWEEPSLGV LKIQNVGWNN
     TAIACAACNN WCSWASPVTL NVLYAPRGVR VRKIKPLSEI HSGNSVSLQC DFSSSHPKEV
     QFFWEKNGSL LGKERQLNFD SISPEDAGSY SCWVNNSMGQ TASKAWTLEV LYAPRRLRVS
     MSQGNQVMEG KTAILTCESD ANPPVSSYTW FDWNNQSLPS SGRMLRLEPV KVQHSGAYWC
     QGTNRVGKGH SPLFTLTVYY SPETIGRRVA VGLGSCLAIL ILAMCGFKVQ RRWTRTQSQQ
     GLQENSSGQS FFVRNKKVRR TPLSEGPHSL GCYNPMIEDG ISYATLRFPE TNTPRTGDAE
     TSEMQRPPPD CDDTVTYSVL QKRQVGDYEN VIPDFSEDEG IHYSELIQFG FGERPQAQEN
     VDYVILKH
//