ID A0A2K5H839_COLAP Unreviewed; 374 AA.
AC A0A2K5H839;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=LRRNT domain-containing protein {ECO:0000259|SMART:SM00013};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000000521.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000000521.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|PIRNR:PIRNR002490}.
CC -!- SIMILARITY: Belongs to the small leucine-rich proteoglycan (SLRP)
CC family. SLRP class I subfamily. {ECO:0000256|ARBA:ARBA00009811,
CC ECO:0000256|PIRNR:PIRNR002490}.
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DR RefSeq; XP_011782850.1; XM_011927460.1.
DR AlphaFoldDB; A0A2K5H839; -.
DR STRING; 336983.ENSCANP00000000521; -.
DR Ensembl; ENSCANT00000002013.1; ENSCANP00000000521.1; ENSCANG00000001746.1.
DR GeneID; 105501482; -.
DR KEGG; cang:105501482; -.
DR CTD; 54829; -.
DR OMA; NRIQKDA; -.
DR OrthoDB; 3953748at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR InterPro; IPR016352; SLRP_I_decor/aspor/byglycan.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF2; ASPORIN; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF01462; LRRNT; 1.
DR PIRSF; PIRSF002490; SLRP_I; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR002490-1};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530,
KW ECO:0000256|PIRNR:PIRNR002490};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..374
FT /note="LRRNT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014401467"
FT DOMAIN 68..100
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DISULFID 69..75
FT /evidence="ECO:0000256|PIRSR:PIRSR002490-1"
FT DISULFID 73..82
FT /evidence="ECO:0000256|PIRSR:PIRSR002490-1"
FT DISULFID 327..360
FT /evidence="ECO:0000256|PIRSR:PIRSR002490-1"
SQ SEQUENCE 374 AA; 42556 MW; CEF898619E22604D CRC64;
MKEYVLLLFL GLCSAKPFFS PSHVALKNMM LKDMEGTDND DDDEEEDNSL FPTKEPRIPF
FPFDLFPMCP FGCQCYSRVV HCSDLGLTSV PANIPFDTRM VDLQNNKIKE IKENDFKGLT
SLYGLILNNN KLTKIHPKAF LTTKKLRRLY LSHNQLSEIP LNLPKSLAEL RIHENKVKKI
QKDTFKGMNA LHVLEMSANP LDNNGIEPGA FEGVTVFHIR IAEAKLTSVP KGLPPTLLEL
HLDYNKISTV ELEDFKRYKE LQRLGLGNNK ITDIENGSLA NIPRVREIHL ENNKLKKIPS
GLPELKYLQI IFLHSNSIAR VGVNDFCPTV AKMKKSLYSA ISLFNNPVKY WEMQPATFRC
VLSRMSVQLG NFGM
//
