ID A0A2K5HBH3_COLAP Unreviewed; 342 AA.
AC A0A2K5HBH3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Aquaporin 7 {ECO:0008006|Google:ProtNLM};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000001688.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000001688.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
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DR RefSeq; XP_011781935.1; XM_011926545.1.
DR RefSeq; XP_011781936.1; XM_011926546.1.
DR AlphaFoldDB; A0A2K5HBH3; -.
DR STRING; 336983.ENSCANP00000001688; -.
DR Ensembl; ENSCANT00000007088.1; ENSCANP00000001688.1; ENSCANG00000006448.1.
DR GeneID; 105500864; -.
DR KEGG; cang:105500864; -.
DR CTD; 364; -.
DR OMA; AYKPHYD; -.
DR OrthoDB; 5490746at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015250; F:water channel activity; IEA:UniProt.
DR GO; GO:0015791; P:polyol transmembrane transport; IEA:UniProt.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR NCBIfam; TIGR00861; MIP; 1.
DR PANTHER; PTHR43829; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR43829:SF15; AQUAPORIN-7; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR02019; AQUAPORIN7.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 37..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 342 AA; 37238 MW; E417189511812F16 CRC64;
MVQTSRHRRS TRGSKMVLWS VIAKIQNTLQ KKMVQEFLAE FMSTYVMMVF GLGSVAHMVL
NQKYGSYLGV NLGFGFGVTM GVHVAGHISG AHMNAAVTFA NCALGRVPWR KFPVYVLGQF
LGSFLAAATI YTLFYTAILH FSGGQLMVTG PVATAGIFAT YLPDHMTLWR GFLNEAWLTG
MLQLCLFAIT DQENNPALPG TQALVIGILV VIIGVSLGMN TGYAINPSRD LPPRVFTFIA
GWGKQVFSEG ENWWWVPVVA PLLGACLGGI IYLVFIGSTI PREPLKLEDS VAYEDHGITV
LPKMGSHEPT ISPLTPVSVS PAIRSSVHPA PPLHESMALE HF
//
