ID A0A2K5HFC5_COLAP Unreviewed; 1277 AA.
AC A0A2K5HFC5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000003015.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000003015.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MCAF family.
CC {ECO:0000256|ARBA:ARBA00010344}.
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DR RefSeq; XP_011809538.1; XM_011954148.1.
DR AlphaFoldDB; A0A2K5HFC5; -.
DR STRING; 336983.ENSCANP00000003015; -.
DR Ensembl; ENSCANT00000012298.1; ENSCANP00000003015.1; ENSCANG00000011112.1.
DR GeneID; 105520419; -.
DR KEGG; cang:105520419; -.
DR CTD; 55729; -.
DR OMA; QETIHEP; -.
DR OrthoDB; 4053704at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026085; ATF7-int.
DR InterPro; IPR031870; ATF7IP_BD.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR23210; ACTIVATING TRANSCRIPTION FACTOR 7 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR23210:SF22; ACTIVATING TRANSCRIPTION FACTOR 7-INTERACTING PROTEIN 1; 1.
DR Pfam; PF16788; ATF7IP_BD; 1.
DR Pfam; PF16794; fn3_4; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50853; FN3; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1167..1277
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 109..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1122..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..968
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1024
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1139..1157
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1277 AA; 137371 MW; 9EB9A4D5AE2E1645 CRC64;
MHQDQRFKMD SLEEPQKKVF KARKTMRVSD RQQLEAVYKV KEELLKTDVK LLNGNHENGD
LDPTSPLENM DYIKDKEEVN GIEEICLDPE ESKTEWKETP CILSVNVKNK QDDDLNCEPL
SPHNIAPEPD SKLTAEPVSG DPVAGDLDAG DPTSGVLASG DSTSGDPTSS EPSSGGAASG
DATSGDAPSG DVSSGDATSG DATADDLSSG NPTSGDPIPG EPVPVEPISG ECAADDIASN
EITSVDLTSG APASTDPASD DLASGDLSSS ELASDDLATG ELASDELTSE SAFDRTFESN
SVPVCEPVPE IDNIEPSSNK DDDFLEKNGV DEKLEQIQSK DSLDEKNKAD NNIDANEETL
ETDDTTICSD RPPENEKKVE EDITELALGE DAISSSIEID QGEKNEDETS ADLVETISEN
VTEDDKSENI LENTDSMETD EIIPILEKLA PSEDELTCFS KTSLLPIDET NPDLEEKMES
SFGSPSKQES SESLPKEAFL VLSDEEDISG EKDESEVISQ NETCSPAEVE SNEKDSKPEE
EEQVIHEEDE RPSEKNEFSR RKRSKSEDMD NVQSKRRRYM EEEYEAEFQV KITAKGDINQ
KLQKVIQWLL EEKLCALQCA VFDKTLAELK TRVEKIECNK RHKTVLTELQ AKIARLTKRF
EAAKEDLKKR HEHPPNPPVS PGKTVNDVNS NNNMPYRNAG TVRQMLESKR NVSESAPPSF
QTPVNTVSST NLVTPPTVVS SQPKLQTPVT SGSLTATSVL PAPNTATVVA TTQVPSGNPQ
PTISLQPLPV ILHVPVAVSS QPQLLQSHPG TLVTNQPSGN VEFISVQSPP TVSGLTKNPV
SLPSLPNPTK PNNIPSVPSS SIQRNPTASA APLGTTLAVQ AVPTAHSIVQ ATRTSLPTVG
PSGLYSPSNN RGPIQMKIPI SAFSTSSPAE QNSNTTPRIE NQTNKTIDAS VNKKAADSTS
QSGKATGSDS GGVIDLTMDD EESGASQDPK KLNHTPVSTM SSSQPVSRPL QPIQPAPPLQ
PSGVPTSGPS QTTIHLLPTA PTTVNVTHRP VTQVTTRLPV PRAPANHQVV YTTLPAPPAQ
APLRGTVMQA PAVRQVNPQN SVTVRVPQTT TYVVNNGLTL GSTGPQLTVH HRPPQVHTEP
PRPMHPAPLP EAPQPQRVPP EAASTSLPQK PHLKLARVQS QNGIVLSWSV LEVDRSCATV
DSYHLYAYHE EPSATVPSQW KKIGEVKALP LPMACTLTQF VSGSKYYFAV RAKDIYGRFG
PFCDPQSTDV ISSTQSS
//
