ID A0A2K5HIE0_COLAP Unreviewed; 639 AA.
AC A0A2K5HIE0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000004113.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000004113.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; A0A2K5HIE0; -.
DR Ensembl; ENSCANT00000016325.1; ENSCANP00000004113.1; ENSCANG00000014451.1.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF51; KIN OF IRRE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 517..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..228
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 233..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 318..400
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 404..507
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..639
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 67356 MW; 104896890DD976BF CRC64;
MSSLGGLQAR DRGSLGWGEE SSAKGAPGQG DRRSASEEEV DGEARATANL VNLGGHTLRM
RVPALLVLLF CFRGSAGWSR YWISGNAANG QHDLHIRPVE LEDEASYECQ ATQAGLRSRP
AQLHVLVPPE APQVLGGPSV SLIAGVPVNL TCRSRGDARP TPELLWFRDG VRLDGTTFHQ
ILLKEGTPGS VESTLTLTPS SHDDGATLVC RARSQALPAG RDTTITLSLK YPPEVTLSAS
PHTVQEGEKV TFLCQATAQP PVTGYRWAKG GSPVLGARGP RLEVVADASF LTEPVSCEVS
NAVGSANRST ALDVLFGPIL QAKPEPVSVD VGEDASFSCA WRGNPLPRVT WTRRGGAQVL
GSGATLRLPS VGPEDAGDYV CRAEPGLSGQ GGGAAEARLT VNAPPVVTAL HSEPAFLRGP
ARLQCLVFAS PAPDAVVWSW DEGFLEAGSR GRFLVETFPA PESRGGQSPG MISVLHISGT
QESDFSRSFN CSARNRLGEG GAQASLGRRD LLPTVRIVAG VAAATTTLLM VITGVALCCW
RHGKASASFS EQKNLMRIPG SSDGCSSRGP EEEETGSRED RGPIVHTDHS DLVLEEEGTL
ETKDPTNGYY KVRGVSPPAS PDSCVTSPQW KSPGISNFP
//
