ID   A0A2K5HPI7_COLAP        Unreviewed;       565 AA.
AC   A0A2K5HPI7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000006263.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000006263.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Sodium-phosphate symporter. {ECO:0000256|RuleBase:RU363058}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 Na(+)(out) + phosphate(out) = 2 Na(+)(in) + phosphate(in);
CC         Xref=Rhea:RHEA:71259, ChEBI:CHEBI:29101, ChEBI:CHEBI:43474;
CC         Evidence={ECO:0000256|ARBA:ARBA00035083};
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363058}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU363058}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000256|ARBA:ARBA00009916,
CC       ECO:0000256|RuleBase:RU363058}.
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DR   AlphaFoldDB; A0A2K5HPI7; -.
DR   Ensembl; ENSCANT00000023614.1; ENSCANP00000006263.1; ENSCANG00000020968.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PHOSPHATE TRANSPORTER; 1.
DR   PANTHER; PTHR11101:SF80; SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363058};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW   ECO:0000256|RuleBase:RU363058};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Sodium {ECO:0000256|ARBA:ARBA00023201};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363058}.
FT   TRANSMEM        20..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        56..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        125..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        398..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        447..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        531..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   REGION          180..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..217
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   565 AA;  61397 MW;  EB82C0A1BD397A3A CRC64;
     MAGEWLEPRS SAVWQLIASF LRLPISGTHC IVGSTIGFSL VAIGTKGVQW MELVKIVASW
     FISPLLSGFM SGLLFVLIRI FILKKEDPVP NGLRALPVFY AATIAINVFS IMYTGAPVLG
     LVLPMWAIAL ISFGVALLFA FFVWLFVCPW MRRKITDKLQ KEGALSRVSD ESLSKVQEAE
     SPVFKELPGA KANDDSTIPL TGAAGETSGT SEGTSAGSHP RAAYGRALSM THGSVKSPVS
     NGTFGFDGHT RSDGHVYHTV HKDSGLYKDL LHKIHIDRGP EEKPAQESNY RLLRRNNSYT
     CYTAAICGLP VHATFRAADS SAAEDSEKLV GDTVSYSKKR LRYDSYSSYC NAVAEAEIEA
     EEGGVEMKLA SELADPDQPQ EDPAEEEKEE KDAPEVHLLF HFLQVLTACF GSFAHGGNDV
     SNAIGPLVAL WLIYKQGGVM QEAATPVWLL FYGGVGICTG LWVWGRRVIQ TMGKDLTPIT
     PSSGFTIELA SAFTVVIASN IGLPVSTTHC KVGSVVAVGW IRSRKAVDWR LFRNIFVAWF
     VTVPVAGLFS AAVMALLMYG ILPYV
//