ID   A0A2K5HPT1_COLAP        Unreviewed;       773 AA.
AC   A0A2K5HPT1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Rho GTPase activating protein 17 {ECO:0008006|Google:ProtNLM};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000006350.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000006350.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5HPT1; -.
DR   Ensembl; ENSCANT00000023941.1; ENSCANP00000006350.1; ENSCANG00000020884.1.
DR   OMA; HAVAXVQ; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR   PANTHER; PTHR14130:SF3; RHO GTPASE-ACTIVATING PROTEIN 17; 1.
DR   Pfam; PF03114; BAR; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   PRINTS; PR01217; PRICHEXTENSN.
DR   SMART; SM00721; BAR; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51021; BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          1..228
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   DOMAIN          234..412
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          428..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..773
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..442
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..503
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        528..542
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        556..577
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..600
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        601..615
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..663
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        686..710
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        713..739
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  83906 MW;  5C1B28D814BF6728 CRC64;
     LRKQKSSHIE RRLDTVRSVC HHSHKRLVAC FQGQHGTDKK HTLSSVFQKK LPLTALAQNM
     QEASTQLEDS LLGKMLETCG DAENQLALEL SQHEVFVEKE IVDPLYGIAE VEIPNIQKQR
     KQLAKLVLDW DSVRARWNQA HKSSGTNFQG LPSKIDTLKE EMDEAGNKVE QCKDQLAADM
     YNFMAKEGEY GKFFVTLLEA QADYHRKALA VLEKTLPEMR AHQDKWAEKP AFGTPLEEHL
     KRSGREIALP IEACVMLLLE TGMKEEGLFR IGAGASKLKK LKAALDCSTS HLDEFYSDPH
     AVAGELGRFC LRQMVFFLSV QDQDKKLQDL WRTCQKLPPQ NFVNFRYLIK FLAKLAQTSD
     VNKMTPSNIA IVLGPNLLWA KNEGTLAEMA AATSVHVVAV IEPIIQHADW FFPEEVEFNV
     SEAFVPLTTP NSNHSSHTGN DSDSGTLERK RPASMAVMEG DLMKKESPPK PKDPASAAAP
     APGRNNSQIA SGQNQTQAAA GSHQLSLGPP HSAAGPSPHT LRRAVKKPAP APPKPGNPPP
     GHPGGQSSSG TSQHPPSLSP KPPTRSPSPP TQHTGQPPGQ PSAPSQLSAP RRYSSSLSPI
     QAPNHPPPQP PTQATPLMHT KPNSQGPPNP MTLPSEHGLE QPSHTPPQTP TPPSTPPLGK
     QNPSLPAPQT LAGGNLETAQ PHAGTLPRPR PVPKPRNRPS VPPPPHPPGV HSAGDSSLTN
     AAPTASKIVT DSNSRVSEPH RSIFPEMHSD SASKDVPGRI LLDIDNDTES TAL
//