ID   A0A2K5HV59_COLAP        Unreviewed;       669 AA.
AC   A0A2K5HV59;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000008207.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000008207.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K5HV59; -.
DR   Ensembl; ENSCANT00000030602.1; ENSCANP00000008207.1; ENSCANG00000027023.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd14674; PH_PLEKHM3_1; 1.
DR   CDD; cd13327; PH_PLEKHM3_2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR037812; PLEKHM3_PH_1.
DR   InterPro; IPR025258; RH_dom.
DR   PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12326:SF10; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          211..308
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          361..456
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   669 AA;  76557 MW;  936463C8AB29630A CRC64;
     MEALEVDDIS PALEVTEEFF STLDSKLEKA VQQAEVYGIQ EVPELVGHEV LSNITDNGAM
     RNVTSLGKGG MIWDHCKSRL LETKAQNVFP AKEQFMVQRG TTPDNLSWME QKEASTFNFF
     NICQRRRDRP RSVNDLLDET STFKPGHARS RSDITQVDWR VVLKTMPLQQ QQQQQPSLQG
     PHVTRPSFLL PSPNKIEDAQ GNTEHKQTFP NILKKGYLEI RKDHDSYWQS CYAELSPYNL
     YFYNLDSSGN QNLYATYQLS HFQSISVLGN LEARMVDTVL YDNTQLQLKA ESPWEALDWG
     QKLWEVVHAA VPGYMGRQNE LTISPGLGHH DDYAQYHYFQ KKASGLLPPS PVLDSPKQYQ
     NILKSGTLYR LTVQNNWKAF TFVLSRAYLM AFQPGKLDED PLLSYNVDVC LAVQMDNLDG
     CDSCFQVIFP QDVLRLRAET RQRAQEWMEA LKTAANAARS SEQNLQVTLR NKPKDQMGGH
     ELRKNKRQSV TTSFLSILTT LSLERGLTAQ SFKCAGCQRS IGLSNGKAKV CNYSGWYYCS
     SCHVDDSFLI PARIVHNWDT SKYKVSKQAK EFLEYVYEEP LIDIQQENAM LYHHAEPLAA
     VLRLRQRLKS LRAYLFSCRA AVAEDLRRRN DQPHALVMLM FLEVKFSPEN TSFNKSTCIP
     SPTCKQHYS
//