ID   A0A2K5HXM1_COLAP        Unreviewed;       630 AA.
AC   A0A2K5HXM1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000009098.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000009098.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   AlphaFoldDB; A0A2K5HXM1; -.
DR   STRING; 336983.ENSCANP00000009098; -.
DR   Ensembl; ENSCANT00000031965.1; ENSCANP00000009098.1; ENSCANG00000027862.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd20052; FH_FOXJ3; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR045912; FOXJ2/3-like.
DR   InterPro; IPR018122; TF_fork_head_CS_1.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46078; FORKHEAD BOX PROTEIN J2 FAMILY MEMBER; 1.
DR   PANTHER; PTHR46078:SF3; FORKHEAD BOX PROTEIN J3; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00657; FORK_HEAD_1; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          86..181
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        86..181
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          152..186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          257..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          324..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..183
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        407..427
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        439..458
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  69756 MW;  8C0DA80993B0E46C CRC64;
     MNNSLCGQMG LYGQACPSVT SLRMTSELES SLTSMDWLPQ LTMRAAIQKS DATQNAHGTG
     ISKKNALLDP NTTLDQEEVQ QHKDGKPPYS YASLITFAIN SSPKKKMTLS EIYQWICDNF
     PYYREAGSGW KNSIRHNLSL NKCFLKVPRS KDDPGKGSYW AIDTNPKEDA LPTRPKKRAR
     SVERASTPYS IDSDSLGMEC IISGSASPTL AINTVTNKVT LYNTDQDGSD SPRSSLNNSL
     SDQSLASVNL NSVGSVHSYT PVTSHPESVS QSLTPQQQPQ YNLPERDKQL LFSEYNFEDL
     SASFRSLYKS VFEQSLSQQG LMNIPSESSQ QSHTSCSYQH SPSSTVSTHP HSNQSSLSNS
     HGSGLNTTGS NSVAQVSLSH PQMHTQPSPH PPHRPHGLPQ HSQRSPHPAP HPQQHSQLQS
     PHPQHPSPHQ HIQHHPNHQH QTLTHQAPPP PQQVSCNSGV SNDWYATLDM LKESCRIASS
     VNWSDVDLSQ FQGLMESMRQ ADLKNWSLDQ VQFADLCSSL NQFFTQTGLI HSQSNVQQNV
     CHGAMHPTKP SQHIGTGNLY IDSRQNLPPS VMPPPGYPHI PQALSTPGTT MAGHHRAMNQ
     QHMMPSQAFQ MRRSLPPDDI QDDFDWDSIV
//