ID A0A2K5I0V8_COLAP Unreviewed; 307 AA.
AC A0A2K5I0V8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000010264.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000010264.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-
CC bisphosphate + an aryl sulfate + H(+); Xref=Rhea:RHEA:12164,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33853, ChEBI:CHEBI:58339,
CC ChEBI:CHEBI:58343, ChEBI:CHEBI:140317; EC=2.8.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00036572};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Lysosome {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR RefSeq; XP_011814888.1; XM_011959498.1.
DR AlphaFoldDB; A0A2K5I0V8; -.
DR STRING; 336983.ENSCANP00000010264; -.
DR Ensembl; ENSCANT00000033151.1; ENSCANP00000010264.1; ENSCANG00000028528.1.
DR GeneID; 105524297; -.
DR CTD; 6819; -.
DR OrthoDB; 3083090at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004062; F:aryl sulfotransferase activity; IEA:UniProt.
DR GO; GO:0051923; P:sulfation; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF73; SULFOTRANSFERASE 1C2; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PRINTS; PR02045; F138DOMAIN.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 39..299
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 307 AA; 35882 MW; D8BA8356E33776D6 CRC64;
MALTSELGKQ IKLKEVEGTL LQPATVDNWS QIQSFEAKPD DLLICTYPKA GTTWIQEIVD
MIEQNGDVEK CQRAIIQHRH PFIEWARPPQ PSETGFHHVA QVGLELLSSS NPPASTSQSA
KITDLLPPSF WENNCKFLYV ARNAKDCIVS YYHFQRMNHM LPDPGTWEEY FETFINGKVV
WGSWFDHVKG WWEMKDRYQI LFLFYEDIKR DPKHEIRKVM QFMGKNLDET VLDTIVQETS
FEKMKENPMT NRSTVSKSIM DQSISSFMRK GTVGDWKNHF TVAQNERFDE IYRKKMEGTS
INFCMEL
//
