ID   A0A2K5I1B0_COLAP        Unreviewed;       508 AA.
AC   A0A2K5I1B0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Gamma-glutamyltransferase 1 {ECO:0008006|Google:ProtNLM};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000010342.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000010342.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the gamma-glutamyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00009381}.
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DR   AlphaFoldDB; A0A2K5I1B0; -.
DR   STRING; 336983.ENSCANP00000010342; -.
DR   Ensembl; ENSCANT00000033230.1; ENSCANP00000010342.1; ENSCANG00000028555.1.
DR   OMA; KATKNMF; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:InterPro.
DR   GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR   Gene3D; 1.10.246.130; -; 1.
DR   Gene3D; 3.60.20.40; -; 2.
DR   InterPro; IPR043138; GGT_lsub_C.
DR   InterPro; IPR000101; GGT_peptidase.
DR   InterPro; IPR043137; GGT_ssub.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   PANTHER; PTHR11686; GAMMA GLUTAMYL TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR11686:SF56; GLUTATHIONE HYDROLASE 1 PROENZYME-RELATED; 1.
DR   Pfam; PF01019; G_glu_transpept; 2.
DR   PRINTS; PR01210; GGTRANSPTASE.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   PROSITE; PS00462; G_GLU_TRANSPEPTIDASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   ACT_SITE        348
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600101-1"
SQ   SEQUENCE   508 AA;  53868 MW;  6E7A708ED1C6EED4 CRC64;
     MKRLVVLGLL AVVLVLVIVG LCLWLPSASK EPDNHVYTRA AVAADAKQCS EIGRDALRDG
     GSAVDAAIAA LLCVGLMNAH SMGIGGGLFL TIYNSTTRKA EVINAREVAP RLAFASMFNS
     SEQSQNGGLS VAVPGEIRGF ELAHQRHGRL PWARLFRPSI QLLSPSHLLT HVSPLCPSEV
     FCRDGKVLRE GERLTLPRLA DTYETLAIEG AQAFYNGSLT AQIVKDIQAA GESVTSGAWV
     RNPAVETLSH GPEPWGPPVL PEPPALAGAP MLLHAPMLFR ADEASKGKLL TVPKPAPSAG
     PALGSRQVVR NMTSEFFAAQ LRALISDDTT HPTSYYKPEF YTPDDGGTSH LSVVAEDGSA
     VSATSTINLY FGSKVRSPVS GILFNDEMDD FSSPSITNQF GVPPSPANFI QPGKQPLSSM
     CPTIMVGQDG QVRMVVGASG GTQITTATAL AWFRWHLEPC SVTAALETRH HHTQIASTFI
     AVVQAIVHTP GGWAAASDSR KGGEPAGY
//