ID A0A2K5I258_COLAP Unreviewed; 116 AA.
AC A0A2K5I258;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Dynein light chain Tctex-type 3 {ECO:0000256|ARBA:ARBA00039901};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000010693.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000010693.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Acts as one of several non-catalytic accessory components of
CC the cytoplasmic dynein 1 complex that are thought to be involved in
CC linking dynein to cargos and to adapter proteins that regulate dynein
CC function. Cytoplasmic dynein 1 acts as a motor for the intracellular
CC retrograde motility of vesicles and organelles along microtubules.
CC Probably binds BUB3 as part of transport cargo. Required for the
CC efficient progression through mitosis. {ECO:0000256|ARBA:ARBA00037393}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the dynein light chain Tctex-type family.
CC {ECO:0000256|ARBA:ARBA00005361}.
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DR RefSeq; XP_011797388.1; XM_011941998.1.
DR AlphaFoldDB; A0A2K5I258; -.
DR Ensembl; ENSCANT00000033584.1; ENSCANP00000010693.1; ENSCANG00000028754.1.
DR GeneID; 105511798; -.
DR CTD; 6990; -.
DR OMA; EEYHRPC; -.
DR OrthoDB; 3679412at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd21463; DLC-like_DYNLT3; 1.
DR Gene3D; 3.30.1140.40; Tctex-1; 1.
DR InterPro; IPR005334; Tctex-1-like.
DR InterPro; IPR038586; Tctex-1-like_sf.
DR PANTHER; PTHR21255:SF20; DYNEIN LIGHT CHAIN TCTEX-TYPE 3; 1.
DR PANTHER; PTHR21255; T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN; 1.
DR Pfam; PF03645; Tctex-1; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nitration {ECO:0000256|ARBA:ARBA00023074};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 116 AA; 13063 MW; 708B27E6FD95F632 CRC64;
MEEYHRHCDE VGFNAEEAHN IVKECVDGVL GGEDYDHNNI NQWTASIVEQ SLTHLVKLGK
AYKYIVTCAV VQKSAYGFHT ASSCFWDTTS DGTCTVRWEN RTMNCIVNVF AIAIVL
//
