ID   A0A2K5I4T0_COLAP        Unreviewed;       648 AA.
AC   A0A2K5I4T0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Agenet-like domain-containing protein {ECO:0000259|PROSITE:PS51641};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000011640.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000011640.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, Cytoplasmic ribonucleoprotein granule
CC       {ECO:0000256|ARBA:ARBA00004331}. Postsynapse
CC       {ECO:0000256|ARBA:ARBA00034110}.
CC   -!- SIMILARITY: Belongs to the FMR1 family.
CC       {ECO:0000256|ARBA:ARBA00006633}.
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DR   AlphaFoldDB; A0A2K5I4T0; -.
DR   STRING; 336983.ENSCANP00000011640; -.
DR   Ensembl; ENSCANT00000034540.1; ENSCANP00000011640.1; ENSCANG00000028959.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0036464; C:cytoplasmic ribonucleoprotein granule; IEA:UniProtKB-SubCell.
DR   GO; GO:0098794; C:postsynapse; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   GO; GO:0006417; P:regulation of translation; IEA:InterPro.
DR   CDD; cd22504; KH_I_FXR1_rpt1; 1.
DR   CDD; cd22507; KH_I_FXR1_rpt2; 1.
DR   CDD; cd22510; KH_I_FXR1_rpt3; 1.
DR   Gene3D; 2.30.30.140; -; 2.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR   InterPro; IPR040148; FMR1.
DR   InterPro; IPR022034; FMR1-like_C_core.
DR   InterPro; IPR040472; FMRP_KH0.
DR   InterPro; IPR032172; FXR1_C1.
DR   InterPro; IPR032177; FXR_C3.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR047494; KH_I_FXR1_rpt1.
DR   InterPro; IPR047495; KH_I_FXR1_rpt2.
DR   InterPro; IPR047496; KH_I_FXR1_rpt3.
DR   InterPro; IPR041560; Tudor_FRM1.
DR   PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10603:SF6; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 1; 1.
DR   Pfam; PF12235; FXMRP1_C_core; 1.
DR   Pfam; PF16096; FXR_C1; 1.
DR   Pfam; PF16097; FXR_C3; 1.
DR   Pfam; PF00013; KH_1; 2.
DR   Pfam; PF17904; KH_9; 1.
DR   Pfam; PF18336; Tudor_FRX1; 1.
DR   SMART; SM00322; KH; 2.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR   PROSITE; PS51641; AGENET_LIKE; 1.
DR   PROSITE; PS50084; KH_TYPE_1; 2.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT   DOMAIN          1..39
FT                   /note="Agenet-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51641"
FT   REGION          351..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        409..444
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        567..581
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..602
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        621..635
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   648 AA;  72940 MW;  D54BDEC37ED39C53 CRC64;
     CFCVLQGFIK DVHEDSLTVV FENNWQPERQ VPFNEVRLPP PPDIKKEISE GDEVEVCIFK
     FFYVIEYAAC DATYNEIVTF ERLRPVNQNK TVKKNTFFKC TVDVPEDLRE ACANENAHKD
     FKKAVGACRI FYHPETTQLM ILSASEATVK RVNILSDMHL RSIRTKLMLM SRNEEATKHL
     ECTKQLAAAF HEEFVVREDL MGLAIGTHGS NIQQARKVPG VTAIELDEDT GTFRIYGESA
     DAVKKARGFL EFVEDFIQVP RNLVGKVIGK NGKVIQEIVD KSGVVRVRIE GDNENKLPRE
     DGMVPFVFVG TKESIGNVQV LLEYHIAYLK EVEQLRMERL QIDEQLRQIG MGFRPSSTRG
     PEKEKGYATD ESTVSSVQGS RSYSGRGRGR RGPNYTSGYG TNSELSNPSE TESERKDELS
     DWSLAGEDDR DSRHQRDSRR RPGGRGRSVS GGRGRGGPRG GKSSISSVLK DPDSNPYSLL
     DNTESDQTAD TDASESHHST NRRRRSRRRR TDEDAVLMDG MTESDTASVN ENGLDDSEKK
     PQRRNRSRRR RFRGQAEDRQ PVTVADYISR AESQSRQRNL PRETLAKNKK EMAKDVIEEH
     GPSEKAINGP TSASGDDISK LQRTPGEEKI NTLKEENTQE AAVLNGVS
//