ID A0A2K5I554_COLAP Unreviewed; 579 AA.
AC A0A2K5I554;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Zinc finger protein 677 {ECO:0008006|Google:ProtNLM};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000011759.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000011759.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K5I554; -.
DR Ensembl; ENSCANT00000034659.1; ENSCANP00000011759.1; ENSCANG00000029254.1.
DR OMA; WENMSKF; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24377; IP01015P-RELATED; 1.
DR PANTHER; PTHR24377:SF1006; ZINC FINGER PROTEIN 141-RELATED; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 10.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 8..90
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 263..290
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 291..318
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 319..346
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 347..374
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 375..402
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 403..430
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 431..458
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 459..486
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 487..514
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 515..542
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 579 AA; 67302 MW; EFCDC3A04BE4B67A CRC64;
MANLFGLFTF KDVAIEFSQE EWECLDPAQR ALYRDVMLEN YRNLLSLDED NIPPENDISV
GFTSKGLSPK ENNKEELYHL VILERKESHG INNFDLKGVW ENMPKFDSLW DYDAKNYKGT
PLTSNKNLTH RKGQQHNKSS IHFSLKQSVS IRDSAYQYFI HDTPFIRNLL KLKNNIRYAG
NKYVKCFENR IGLSLQAQLT ERQSFQTGEK MYECNPVEKS INSSSVSPLP PCVKNICNKY
RKILKYPLLH TQYGRTHIRE KSYKCNDCGK AFSKSSNLTN HQRIHSGQRP YKCKECGKAF
NQCSNLTRHQ RVHTGEKPYQ CNICGKVCSQ NSNLASHQRM HTGEKPYKCN ECGKAFIQRS
HLWGHERIHT GEKPYKCSEC DKAFAERSSL TQHKRIHTGE KPYICNECGK AFKQCSHLTR
HQNIHPGEKP HKCHVCGKAF IQSSSLVEHQ RIHTGEKPYK CNKCDKAFIK RSHLWGHQRT
HTGEKPYKCT ECGKAFTERS NLTQHKKIHT GEKPYKCTEC GKAFTQFANL TRHQKIHIEK
KHCKHNIHGN ALFQSSNLGD HQKIYDREKC IKYNETKIK
//
