ID   A0A2K5I609_COLAP        Unreviewed;       453 AA.
AC   A0A2K5I609;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Transmembrane serine protease 6 {ECO:0008006|Google:ProtNLM};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000012068.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000012068.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR   AlphaFoldDB; A0A2K5I609; -.
DR   Ensembl; ENSCANT00000034970.1; ENSCANP00000012068.1; ENSCANG00000029400.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.960; SEA domain; 1.
DR   Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR000082; SEA_dom.
DR   InterPro; IPR036364; SEA_dom_sf.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   Pfam; PF01390; SEA; 1.
DR   SUPFAM; SSF82671; SEA domain; 1.
DR   SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR   PROSITE; PS01180; CUB; 1.
DR   PROSITE; PS50024; SEA; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        53..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          82..207
FT                   /note="SEA"
FT                   /evidence="ECO:0000259|PROSITE:PS50024"
FT   DOMAIN          333..395
FT                   /note="CUB"
FT                   /evidence="ECO:0000259|PROSITE:PS01180"
FT   REGION          13..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   453 AA;  50894 MW;  931AD18CE92A96E5 CRC64;
     TLLLFHSKRM PVAKAPQVAG GQGDGGDGEE AEPEGMFKAR EDSKRKARGY LRLAPLWLTL
     VVLTSVGVLL WYFLGYKAEV TVSQVYSGSL RVLNRHFSQD LTRRESSAFR SETAKAQKML
     KELIASTRLG TYYNSSSVYS FGEGPLTCFF WFILQIPEHR RPMLSPEVVQ ALLVEELLST
     VNSSAAVPYR AEYEVDPEGL VILEASVKDI AALNSTLGCY RYSYVGQGQV LRLKGPDHLA
     SSCLWHLQGP EDLMLKLRLE WMLAECRDRL AMYDVAGPLE KRLITSVYGC SRQEPVVEVL
     ASGAIMAVVW KKGLHSYYDP FMLSVQPVVF QACEVNLTLD DRLDFQGVLS TPYFPSYYSP
     RTHCSWHLTV PSLDYGLALW FDAYALRRQK YDLPCTQGQW TIQNRRYYFL SSLQLPFLPP
     PPSPPSPTVT PSLEAQVPSL RGAAGGAWSW CWA
//