ID   A0A2K5I6U2_COLAP        Unreviewed;       235 AA.
AC   A0A2K5I6U2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=DED domain-containing protein {ECO:0000259|PROSITE:PS50168};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000012349.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000012349.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011805326.1; XM_011949936.1.
DR   AlphaFoldDB; A0A2K5I6U2; -.
DR   Ensembl; ENSCANT00000035255.1; ENSCANP00000012349.1; ENSCANG00000029548.1.
DR   GeneID; 105517408; -.
DR   CTD; 841; -.
DR   OrthoDB; 2873736at2759; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd08333; DED_Caspase_8_r1; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR   InterPro; IPR033170; Caspase-8_DED1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001875; DED_dom.
DR   PANTHER; PTHR48169:SF4; CASP8 AND FADD LIKE APOPTOSIS REGULATOR; 1.
DR   PANTHER; PTHR48169; DED DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01335; DED; 2.
DR   SMART; SM00031; DED; 2.
DR   SUPFAM; SSF47986; DEATH domain; 2.
DR   PROSITE; PS50168; DED; 2.
PE   4: Predicted;
KW   Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          2..80
FT                   /note="DED"
FT                   /evidence="ECO:0000259|PROSITE:PS50168"
FT   DOMAIN          100..177
FT                   /note="DED"
FT                   /evidence="ECO:0000259|PROSITE:PS50168"
FT   REGION          185..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..217
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   235 AA;  27528 MW;  1A33EDF570AC4F2A CRC64;
     MDFSRNLYDI GEQLDSEDLA SLKFLSLDCI PQRKQEPIKD ALMLFRRLQE KRMLEENNLS
     FLKELLFRIN RLDLLTTYLN TRKEEMEREL RAPGRAQISA YRVMLYQISE EVSRSELRSF
     KFLLQEEISK CKLDDDMNLL DIFIEMEKRV ILGEGKLDIL KRVCAQVNKS LLKIINGYEE
     FSRERTRSLE GSPDEGSNDF GQSLPNEKQT SGILSDHQQL RFYKSTGESA QTSQH
//