ID A0A2K5ID42_COLAP Unreviewed; 680 AA.
AC A0A2K5ID42;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=WH2 domain-containing protein {ECO:0000259|PROSITE:PS51082};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000014545.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000014545.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR AlphaFoldDB; A0A2K5ID42; -.
DR STRING; 336983.ENSCANP00000014545; -.
DR Ensembl; ENSCANT00000037474.1; ENSCANP00000014545.1; ENSCANG00000030722.1.
DR OMA; IQFYEIQ; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR InterPro; IPR031738; JMY/WHAMM.
DR InterPro; IPR031808; JMY/WHAMM_N.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR23330; P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED; 1.
DR PANTHER; PTHR23330:SF6; WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES; 1.
DR Pfam; PF15871; JMY; 1.
DR Pfam; PF15920; WHAMM-JMY_N; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT DOMAIN 610..627
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 402..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 347..374
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 402..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..547
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 77318 MW; 2B915FF555069A4B CRC64;
MEDEQPDSLE GWVPVREGLF AEPERHRLRF LVAWNGAGGR RRPRAPRCPH LRWTAAGNRR
GPAKLEPSVL AARSWTRPLT FALKMLAEQD VATGNARNIV IQGHGKANTM VALMKLYQEE
DEAYQELVTV ATMFFQYLLQ PFRAMREVAT LCKLDILKSL DEDDLGPRRV VALEKEAEEW
TRRAEEAVVS IQDITVNYFK ETVKALAVMR KEMEQDAKRF GQAAWATAIP RMEKLKQMLA
RETLQLMRAK ELCLNHKRAE IQGKMEDLPE QEKNINVVDE LEIQFYEIQL ELYEVKFEIL
KNEEILLTTQ LDSLKRLIKE KQNEVVYYDP CESPEELKVI DCVVGLQDDK NLEVKELRRQ
CQQLESKRGR ICAKRASLRS RKDQCKENHR LRLQQAEESI RYSRQHHSIQ MKRDKIKEEE
QKKKEWINQE RQKTLQRLRT FKDKRLAQSV QNTSGSEPVA PNLPGNLSQQ TCLPASQAVS
VIHPSSRKTR GVPLSEAGNV KSPKCQDCHG NIPVQVFVPV GDQTHSKSSE ELSLPPPPPP
PPPLPALSSS SQAATHQNLV CESPAERPRD SLESFPCPGS MDEVLASLRH GRAPLRKVEV
PAVRPPHASI NEHILAAIRQ GVKLKKVHPD LGQNLSSKPT SSRHTSDLER SIKAALQRIK
RVSAGSEEDS DEQDPGQWDG
//
