ID   A0A2K5IGS0_COLAP        Unreviewed;      1084 AA.
AC   A0A2K5IGS0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=L-fucokinase domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000015746.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000015746.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GHMP kinase family.
CC       {ECO:0000256|ARBA:ARBA00038121}.
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DR   RefSeq; XP_011817554.1; XM_011962164.1.
DR   RefSeq; XP_011817562.1; XM_011962172.1.
DR   AlphaFoldDB; A0A2K5IGS0; -.
DR   STRING; 336983.ENSCANP00000015746; -.
DR   Ensembl; ENSCANT00000038682.1; ENSCANP00000015746.1; ENSCANG00000031310.1.
DR   GeneID; 105526227; -.
DR   KEGG; cang:105526227; -.
DR   CTD; 197258; -.
DR   OMA; QKMFSYC; -.
DR   OrthoDB; 5800at2759; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProt.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.230.120; -; 1.
DR   InterPro; IPR012887; Fucokinase.
DR   InterPro; IPR013750; GHMP_kinase_C_dom.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR006204; GHMP_kinase_N_dom.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   PANTHER; PTHR32463; L-FUCOSE KINASE; 1.
DR   PANTHER; PTHR32463:SF0; L-FUCOSE KINASE; 1.
DR   Pfam; PF07959; Fucokinase; 1.
DR   Pfam; PF08544; GHMP_kinases_C; 1.
DR   Pfam; PF00288; GHMP_kinases_N; 1.
DR   PRINTS; PR00959; MEVGALKINASE.
DR   SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          92..496
FT                   /note="L-fucokinase"
FT                   /evidence="ECO:0000259|Pfam:PF07959"
FT   DOMAIN          828..889
FT                   /note="GHMP kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00288"
FT   DOMAIN          971..1046
FT                   /note="GHMP kinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08544"
SQ   SEQUENCE   1084 AA;  117772 MW;  730726571E4C2F69 CRC64;
     MEQPKGVDWT VIILTCQYKD SVQIFQRELE VRQKREQIPA GTLLLAVEDP EKRVGSGGAT
     LNALLVAAEH LSARAGFTVV TSDVLHSAWI LILHMGRDFP FDDCGRAFTC LPMENSEAPV
     EALVCNLDCL LDIMTYRLGP GSPPGVWVCS TDMLLSVPVN PGISWDSFQG ARVIALPGSL
     AYARNHGVYL TDPQGLVLDI YYQGTEAEIQ RCVRPDGRVP LVSGVVFFSV ETAERLLATH
     VSPPLDACTY LGLDSGARPV QLSLFFDILY CMAENVTRED FLVGRPPELG QGDADVAGYL
     QSARAQLWRE LRDQPLTMAY VSNGSYSYMT SSATEFLHSL ARPGAPGAQI VHSQVEEQQL
     LAAGSSVVSC LLEGPVRLGP GSVLQHCHLR GPIHIGAGCM VSGLDIAHSE ALRGRELHDL
     VLQGHHTRLH GSPGHAFTLV GRLDSWERHG AGTYLNVPWS EFFKRTGVRA WDLWDPDTLP
     AECCLPSARL FPVLHPSRDL GPQDLLWMLD RQEDGGEALR AWRASWRLSW EQLQPCLDRA
     ATLASRRDLF FRQALHKARH VLEARQDLSL RPLIWAAVRE GCPGPLLATL DQVAAGAGDP
     GVAARALACV ADVLGCMAEG RGGLRSGPAA NPEWMRPFSY LECGDLAAGV EALAQERDKW
     LSRPALLVRA ARHYEGAGQI LIRQAVMSAQ HFVSTEPVEL PGPGQWVVAE CPARVDFSGG
     WSDTPPLAYE LGGAVLGLAV RVDGRRPIGA RARRIPEPEL WLAVGPRQDE MTVKIVCRCL
     ADLRDYCQPH APGALLKAAF ICAGIVHVHS ELQLNEQLLR TFGGGFELHT WSELPHGSGL
     GTSSILAGTA LAALQRAAGR VVGTEALIHA VLHLEQVLTT GGGWQDQVGG LMPGIKVGRS
     RAQLPLKVEV EEVTVPEGFV QKLNDHLLLV YTGKTRLARN LLQDVLRSWY ARLPAVVQNA
     HSLVQQTEEC AEAFRQGSLP LLGQCLTSYW EQKKLMAPGC EPLAVRRMMD VLAPHVHGQS
     LAGAGGGGFL YLLTKEPQQK EALEAVLAKT EGLGNYSIHL VEVDTQGLSL KLLGTEASTC
     CPFP
//