ID A0A2K5IGS2_COLAP Unreviewed; 3114 AA.
AC A0A2K5IGS2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 10-FEB-2021, entry version 17.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000015859};
GN Name=CENPF {ECO:0000313|Ensembl:ENSCANP00000015859};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000015859, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000015859}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hughes D.S., Murali S., Raveendran M., Korchina V., Bandaranaike D.,
RA Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H., Doddapaneni H.,
RA Gnanaolivu R., Gross S., Jayaseelan J., Jones J., Khan Z., Kovar C.,
RA Kurapati P., Le B., Lee S., Mathew T., Narasimhan A., Okwuonu G.,
RA Ongeri F., Osuji N., Qu C., Quiroz J., Rajbhandari K., Reid J.G.,
RA Santibanez J., Skinner E., Wang Y., Xin Y., Han Y., Muzny D.M.,
RA Richards S., Worley K.C., Rogers J., Gibbs R.A.;
RT "Black and white colobus reference genome project.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCANP00000015859}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2018) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011784804.1; XM_011929414.1.
DR RefSeq; XP_011784805.1; XM_011929415.1.
DR Ensembl; ENSCANT00000038795; ENSCANP00000015859; ENSCANG00000031380.
DR GeneID; 105502776; -.
DR CTD; 1063; -.
DR GeneTree; ENSGT00730000111187; -.
DR OMA; YNAQLVQ; -.
DR OrthoDB; 205405at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1893..2035
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2131..2270
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2313..2452
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2970..3013
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 208..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1162..1186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1667..1688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2889..3114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 418..501
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 546..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..650
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 658..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..745
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 832..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..957
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 962..996
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1196..1244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1286..1313
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1397..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1549..1612
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1624..1646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1817
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1825..1845
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1853..1873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1904..1997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2002..2078
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2107..2134
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2142..2278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2296..2316
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2324..2360
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2366..2467
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2475..2544
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2576..2603
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2618..2638
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2650..2684
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2689..2716
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2739..2773
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2781..2825
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2836..2863
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2928..2956
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2962..2984
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2999..3013
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3029..3080
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3114 AA; 357799 MW; 8E622DFAC5852E3B CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQTLPQT TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQKTPIRRD
FSASYFSGEQ GVTPSRSTLQ IGKRDANSSF FDNSSSPHLL EQLKVQNQEL RSKINELELH
LQGQEKEMKG QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRATAQY DQASTKCTAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECIQVKAR
LTQELQQAKN MHNVLQAELD KVTAVKQQLE KNLEEFKQKL CRAEQASQAS QIKEDELRRS
VEEMKKENNL LKSQSEQKTR EVCHLEAELK NVKQCLNQSQ NFAEEMKVKN TSQETMLRDL
HEKINQQENS LTLEKLKLAV AELEKQRDCS QDLLKKREHH IEQLNDKLSK TEKESKALLS
ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKENL QSKINHLETC LKTQQIKSHE
YNERVRTLEM DRENLSVEIR NLHNVIDSKS VEVETQKLAY VELQQKAEFS DQKHQKEIEN
MCLKTSQLTG QVEDLEHKLQ LLSNEIMDKD RCYQDLHAEY ESLRDLLKSR DVSLATNEDH
QRSLLAFDEQ PAMHNSFANI IEDQGSMPSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
ETLSALENKE KELQLLNGKL ETEQAEIQEL KQSNHLLEDS LKELQLLSET LSLEKKEMSS
IISLNKREIE QLTQENETLK EINASLNQEK MNLIQKSESF ANYIDEREKS ISELSDQYKQ
EKLILLQRCE ETGNAYEALS QKYKAAQEKN SKLECLLNEC TSLCENRKNE LEQLKEAFAK
EHQEFLTKLA FAEERNQNLM LELETVQQDL RSEMTDTQNN SKSETDGLKQ EIMTLKEEQN
KMQKEVNDLL QENEQLMKVM KTKHECQNPE SEPIRNSVKE RESERNQCNF KPQMDLEVKE
ISLDSYNAQL VQLEAMLRNM ELKLQESEKE KECLQHELQI IRGDLETKNL QDMQSQEISG
LKDCEVDAEE RYIPVLHELS TSQNDNAHLE CSLQTAMNKL NELEKICEIL QAEKCELVTE
LNDSRSECIT ATRKMAEEVG KLVNEVKILN EDSGLLHGEL VEDLPGGEFG EQPNEQHPMC
LAPLDESNSY EHLTLSNKEV QIHFAELQEK FSSLQSEHKI LYDQHCQMSS KMSELQTYID
SLKAENLVLS TNLRNFQGDL VKEMQPGLEE GLVPSLSSSC VPDSPGLSSL GDSSFYKALL
EQTGEMSLLN NLEGTVSANQ CSVDEVFCSS LEEENLTKKE TPSAPAKGVE ELESLCEAYR
QSLEKLEEKM ESQGIMKNKE IQELEQLLSS ERQELDCLRK QYLSENEQWQ QKLTSVTLEM
ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES CDVSKEHTSE
TTERTPKHDV HQICDKDVQQ DLHLDIEKIT ETGAVKLTGE CSGEQYPDTN YETPGEDKTQ
GSSECISELS FSGANASIPM DFPGNQENIQ NLQLRVKETS NENLRLLHVI EERDRKVESL
LNEMKELDSK LHLQEVQLMT KIEACIELEK IVGELKKENS ELSEKLEYFS CDNQELLQRV
ESSEGLNSNL EMRADKSSHE DIDDNVAKVN DSWKERFLVV ENELSRIRSE KANIEHQALS
LEADLEIVQT ERLCLEKDNE NKQKVIVCLE EELSVVTSER NQLRGELDTM SKKNTELDQL
SEKMKEKTQE LESHRSEYLH CIQVAEAEVK EKTELLQTLS SDVSELLKDK THLQEKLQSL
EKDSQALSLT KCELENQIAQ LNKEKELLIK ESESLQTRLN ESDYEKLNIS KALEAALVEK
GEFVLRLSST QEEVHQLRRG IEKLRVRIEA DERKQLHIAE KLKEREREND SLKDKVENLE
RELQMSEENQ ELVILDAENS KAEVETLKTQ IEEMARNLKV FELDLVTLRS EKENLTKQIQ
EKQGQVSELD KLLSSFKSLL EEKEQAEIQI KEESKTAVEM LQNQLKELNE AVAALCGDQE
TMKATEQSLD PPVEEAHQLR NSIEKLRSRL ETDEKKQLCV LEQLKESEHH ADLLKSRVEN
LERELEIARK NQEHAALEAE SSKGEVETLK AKIEGMTQSL RELELDLATI RSEKENLTNK
LQKEQERISE LEIINSSFEN ILREKEQEKV EMKEKSNTAM EMLQAQLKEL NERVTALHND
QEACKAKEQN LSSQVDCLEL EKAQLLQGLD EAKNNNIVLQ SSVNGLIQEV EDGKQKLGKK
DEEISRLKNQ IQDQEQLISK LSQVEGEHQL WKKQNLELGN LTVELEQKIQ VLHSKNASLQ
DTLEVLQGSY KNLENELELT KMDKMSFVEK VNTMTAKETE LQREMHEMAQ KTTELQEELS
GETNRLTGEL QLLLEEIKSS KDQLKELTLE NSELKKSLDC MHKDQVEKEG KVREEIAEYQ
LRLHETEKKH QALLLDTNKQ YEIEIHTYRE KLTSKEECLN SQKLEMDLLK SSKEELNNSL
KATTQVLEEL KKTKMDNLKY VNQLKKENEH AQGKIKLLIK SCKQLEEEKE ILQKELSKLQ
AAQEKQKTGT VVDTKVDELT TEIKKLKEAL EEKTKEADEY LDKYCSLLIS HEKLEKAKEM
LETQVAHLCS QQSKPDSRGS PLLDPVVPGP SPILSAAEKR LSSGQKKASG KRQRSSGIWE
NGRGPTPSTP ETFSKKSKKA VMSGIHPAED TEGTEFEPEG LPEVVKKGFA DIPTGKTSPY
ILRRTTMATR TSPRLAAQKL ALSPLSLGKE NLAESSKPTA GGSRSQKVKV AQQNPVDSDT
ILREPTTKSL PVNNLPERSP TDSPREGLRV KRGRLAPNPK AGLEPKGSEN CKVQ
//
