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Database: UniProt
Entry: A0A2K5IGS2_COLAP
LinkDB: A0A2K5IGS2_COLAP
Original site: A0A2K5IGS2_COLAP 
ID   A0A2K5IGS2_COLAP        Unreviewed;      3114 AA.
AC   A0A2K5IGS2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   10-FEB-2021, entry version 17.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000015859};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSCANP00000015859};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000015859, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000015859}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hughes D.S., Murali S., Raveendran M., Korchina V., Bandaranaike D.,
RA   Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H., Doddapaneni H.,
RA   Gnanaolivu R., Gross S., Jayaseelan J., Jones J., Khan Z., Kovar C.,
RA   Kurapati P., Le B., Lee S., Mathew T., Narasimhan A., Okwuonu G.,
RA   Ongeri F., Osuji N., Qu C., Quiroz J., Rajbhandari K., Reid J.G.,
RA   Santibanez J., Skinner E., Wang Y., Xin Y., Han Y., Muzny D.M.,
RA   Richards S., Worley K.C., Rogers J., Gibbs R.A.;
RT   "Black and white colobus reference genome project.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCANP00000015859}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
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DR   RefSeq; XP_011784804.1; XM_011929414.1.
DR   RefSeq; XP_011784805.1; XM_011929415.1.
DR   Ensembl; ENSCANT00000038795; ENSCANP00000015859; ENSCANG00000031380.
DR   GeneID; 105502776; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1893..2035
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2131..2270
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2313..2452
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2970..3013
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          208..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1162..1186
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1667..1688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2889..3114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          386..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..501
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          546..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..650
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          658..685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..745
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          832..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..957
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          962..996
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1029..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1196..1244
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1286..1313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1397..1417
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1549..1612
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1624..1646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1790..1817
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1825..1845
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1853..1873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1904..1997
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2002..2078
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2107..2134
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2142..2278
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2296..2316
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2324..2360
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2366..2467
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2475..2544
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2576..2603
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2618..2638
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2650..2684
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2689..2716
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2739..2773
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2781..2825
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2836..2863
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        2928..2956
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2962..2984
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2999..3013
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3029..3080
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3114 AA;  357799 MW;  8E622DFAC5852E3B CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
     EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQTLPQT TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQKTPIRRD
     FSASYFSGEQ GVTPSRSTLQ IGKRDANSSF FDNSSSPHLL EQLKVQNQEL RSKINELELH
     LQGQEKEMKG QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRATAQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECIQVKAR
     LTQELQQAKN MHNVLQAELD KVTAVKQQLE KNLEEFKQKL CRAEQASQAS QIKEDELRRS
     VEEMKKENNL LKSQSEQKTR EVCHLEAELK NVKQCLNQSQ NFAEEMKVKN TSQETMLRDL
     HEKINQQENS LTLEKLKLAV AELEKQRDCS QDLLKKREHH IEQLNDKLSK TEKESKALLS
     ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKENL QSKINHLETC LKTQQIKSHE
     YNERVRTLEM DRENLSVEIR NLHNVIDSKS VEVETQKLAY VELQQKAEFS DQKHQKEIEN
     MCLKTSQLTG QVEDLEHKLQ LLSNEIMDKD RCYQDLHAEY ESLRDLLKSR DVSLATNEDH
     QRSLLAFDEQ PAMHNSFANI IEDQGSMPSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
     ETLSALENKE KELQLLNGKL ETEQAEIQEL KQSNHLLEDS LKELQLLSET LSLEKKEMSS
     IISLNKREIE QLTQENETLK EINASLNQEK MNLIQKSESF ANYIDEREKS ISELSDQYKQ
     EKLILLQRCE ETGNAYEALS QKYKAAQEKN SKLECLLNEC TSLCENRKNE LEQLKEAFAK
     EHQEFLTKLA FAEERNQNLM LELETVQQDL RSEMTDTQNN SKSETDGLKQ EIMTLKEEQN
     KMQKEVNDLL QENEQLMKVM KTKHECQNPE SEPIRNSVKE RESERNQCNF KPQMDLEVKE
     ISLDSYNAQL VQLEAMLRNM ELKLQESEKE KECLQHELQI IRGDLETKNL QDMQSQEISG
     LKDCEVDAEE RYIPVLHELS TSQNDNAHLE CSLQTAMNKL NELEKICEIL QAEKCELVTE
     LNDSRSECIT ATRKMAEEVG KLVNEVKILN EDSGLLHGEL VEDLPGGEFG EQPNEQHPMC
     LAPLDESNSY EHLTLSNKEV QIHFAELQEK FSSLQSEHKI LYDQHCQMSS KMSELQTYID
     SLKAENLVLS TNLRNFQGDL VKEMQPGLEE GLVPSLSSSC VPDSPGLSSL GDSSFYKALL
     EQTGEMSLLN NLEGTVSANQ CSVDEVFCSS LEEENLTKKE TPSAPAKGVE ELESLCEAYR
     QSLEKLEEKM ESQGIMKNKE IQELEQLLSS ERQELDCLRK QYLSENEQWQ QKLTSVTLEM
     ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES CDVSKEHTSE
     TTERTPKHDV HQICDKDVQQ DLHLDIEKIT ETGAVKLTGE CSGEQYPDTN YETPGEDKTQ
     GSSECISELS FSGANASIPM DFPGNQENIQ NLQLRVKETS NENLRLLHVI EERDRKVESL
     LNEMKELDSK LHLQEVQLMT KIEACIELEK IVGELKKENS ELSEKLEYFS CDNQELLQRV
     ESSEGLNSNL EMRADKSSHE DIDDNVAKVN DSWKERFLVV ENELSRIRSE KANIEHQALS
     LEADLEIVQT ERLCLEKDNE NKQKVIVCLE EELSVVTSER NQLRGELDTM SKKNTELDQL
     SEKMKEKTQE LESHRSEYLH CIQVAEAEVK EKTELLQTLS SDVSELLKDK THLQEKLQSL
     EKDSQALSLT KCELENQIAQ LNKEKELLIK ESESLQTRLN ESDYEKLNIS KALEAALVEK
     GEFVLRLSST QEEVHQLRRG IEKLRVRIEA DERKQLHIAE KLKEREREND SLKDKVENLE
     RELQMSEENQ ELVILDAENS KAEVETLKTQ IEEMARNLKV FELDLVTLRS EKENLTKQIQ
     EKQGQVSELD KLLSSFKSLL EEKEQAEIQI KEESKTAVEM LQNQLKELNE AVAALCGDQE
     TMKATEQSLD PPVEEAHQLR NSIEKLRSRL ETDEKKQLCV LEQLKESEHH ADLLKSRVEN
     LERELEIARK NQEHAALEAE SSKGEVETLK AKIEGMTQSL RELELDLATI RSEKENLTNK
     LQKEQERISE LEIINSSFEN ILREKEQEKV EMKEKSNTAM EMLQAQLKEL NERVTALHND
     QEACKAKEQN LSSQVDCLEL EKAQLLQGLD EAKNNNIVLQ SSVNGLIQEV EDGKQKLGKK
     DEEISRLKNQ IQDQEQLISK LSQVEGEHQL WKKQNLELGN LTVELEQKIQ VLHSKNASLQ
     DTLEVLQGSY KNLENELELT KMDKMSFVEK VNTMTAKETE LQREMHEMAQ KTTELQEELS
     GETNRLTGEL QLLLEEIKSS KDQLKELTLE NSELKKSLDC MHKDQVEKEG KVREEIAEYQ
     LRLHETEKKH QALLLDTNKQ YEIEIHTYRE KLTSKEECLN SQKLEMDLLK SSKEELNNSL
     KATTQVLEEL KKTKMDNLKY VNQLKKENEH AQGKIKLLIK SCKQLEEEKE ILQKELSKLQ
     AAQEKQKTGT VVDTKVDELT TEIKKLKEAL EEKTKEADEY LDKYCSLLIS HEKLEKAKEM
     LETQVAHLCS QQSKPDSRGS PLLDPVVPGP SPILSAAEKR LSSGQKKASG KRQRSSGIWE
     NGRGPTPSTP ETFSKKSKKA VMSGIHPAED TEGTEFEPEG LPEVVKKGFA DIPTGKTSPY
     ILRRTTMATR TSPRLAAQKL ALSPLSLGKE NLAESSKPTA GGSRSQKVKV AQQNPVDSDT
     ILREPTTKSL PVNNLPERSP TDSPREGLRV KRGRLAPNPK AGLEPKGSEN CKVQ
//
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