ID   A0A2K5IHS6_COLAP        Unreviewed;       173 AA.
AC   A0A2K5IHS6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Transmembrane protein 208 {ECO:0000256|ARBA:ARBA00015033};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000016219.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000016219.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: May function as a negative regulator of endoplasmic
CC       reticulum-stress induced autophagy. {ECO:0000256|ARBA:ARBA00003220}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TMEM208 family.
CC       {ECO:0000256|ARBA:ARBA00009950}.
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DR   AlphaFoldDB; A0A2K5IHS6; -.
DR   STRING; 336983.ENSCANP00000016219; -.
DR   Ensembl; ENSCANT00000039155.1; ENSCANP00000016219.1; ENSCANG00000031528.1.
DR   OMA; PIRAGWM; -.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008506; SND2/TMEM208.
DR   PANTHER; PTHR13505; TRANSMEMBRANE PROTEIN 208; 1.
DR   PANTHER; PTHR13505:SF7; TRANSMEMBRANE PROTEIN 208; 1.
DR   Pfam; PF05620; TMEM208_SND2; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          152..173
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   173 AA;  19614 MW;  34C4E46D161067BE CRC64;
     MAPKGKVGTR GKKQIFEENK ETLKFYLRII LGANAIYCLV TLVFFYSSAS FWAWLALGFS
     LAVYGASYHS MSSMARAAFS EDGALMDGGM DLNMEQGMAE HLKDVILLTA IVQVLSCFSL
     YVWSFWLLAP GRALYLLWVN VLGPWFTADS GTPAPEHNEK RQRRQERRQM KRL
//