ID A0A2K5IJH0_COLAP Unreviewed; 380 AA.
AC A0A2K5IJH0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=HotDog ACOT-type domain-containing protein {ECO:0000259|PROSITE:PS51770};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000016814.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000016814.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011793667.1; XM_011938277.1.
DR AlphaFoldDB; A0A2K5IJH0; -.
DR Ensembl; ENSCANT00000039755.1; ENSCANP00000016814.1; ENSCANG00000031815.1.
DR GeneID; 105509161; -.
DR KEGG; cang:105509161; -.
DR CTD; 11332; -.
DR OrthoDB; 5393604at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR CDD; cd03442; BFIT_BACH; 2.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 2.
DR InterPro; IPR040170; Cytosol_ACT.
DR InterPro; IPR033120; HOTDOG_ACOT.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR006683; Thioestr_dom.
DR PANTHER; PTHR11049; ACYL COENZYME A THIOESTER HYDROLASE; 1.
DR PANTHER; PTHR11049:SF27; CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE; 1.
DR Pfam; PF03061; 4HBT; 2.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
DR PROSITE; PS51770; HOTDOG_ACOT; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01106};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487}.
FT DOMAIN 50..168
FT /note="HotDog ACOT-type"
FT /evidence="ECO:0000259|PROSITE:PS51770"
FT DOMAIN 224..338
FT /note="HotDog ACOT-type"
FT /evidence="ECO:0000259|PROSITE:PS51770"
FT REGION 350..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 66
FT /evidence="ECO:0000256|PIRSR:PIRSR640170-1"
FT ACT_SITE 255
FT /evidence="ECO:0000256|PIRSR:PIRSR640170-1"
SQ SEQUENCE 380 AA; 41824 MW; 3B287F7075FC7630 CRC64;
MKLLARALRL CEFGRQASSR RLVAGQGCVG PRRGCCAPIQ VVGPRADLPP SGACITGRIM
RPDDANVAGN VHGGTILKMI EEAGAIISTR HCNSQNGERC VAALARVERT DFLSPMCIGE
VAHVSAEITY TSKHSVEVQV NVMSENILTG AKKLTNKATL WYVPLSLKNV DKVLEVPPVV
YSRQEQEEEG RKRYEAQKLE RMETKWRNGD IVQPVLNPEP NTVSYSQSSL IHLVGPSDCT
LHGFVHGGVT MKLMDEVAGI VAARHCKTNI VTASVDAINF HDKIRKGCVI TISGRMTFTS
NKSMEIEVLV DADPVVDSSQ KRYRAASAFF TYVSLSQEGR SLPVPQLVPE TEDEKKRFEE
GKGRYLQMKA KRQGHTEPQP
//
