ID A0A2K5IT75_COLAP Unreviewed; 303 AA.
AC A0A2K5IT75;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Longin domain-containing protein {ECO:0000259|PROSITE:PS50859};
OS Colobus angolensis palliatus (Peters' Angolan colobus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Colobinae; Colobus.
OX NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000019687.1, ECO:0000313|Proteomes:UP000233080};
RN [1] {ECO:0000313|Ensembl:ENSCANP00000019687.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in vesicle transport between the ER and the
CC Golgi complex. {ECO:0000256|ARBA:ARBA00003595}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00008025}.
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DR RefSeq; XP_011806344.1; XM_011950954.1.
DR RefSeq; XP_011806345.1; XM_011950955.1.
DR AlphaFoldDB; A0A2K5IT75; -.
DR STRING; 336983.ENSCANP00000019687; -.
DR Ensembl; ENSCANT00000042652.1; ENSCANP00000019687.1; ENSCANG00000033271.1.
DR GeneID; 105518102; -.
DR KEGG; cang:105518102; -.
DR CTD; 9117; -.
DR OrthoDB; 129635at2759; -.
DR Proteomes; UP000233080; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR043546; Sec22a/c.
DR PANTHER; PTHR46258; LONGIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46258:SF2; VESICLE-TRAFFICKING PROTEIN SEC22C; 1.
DR Pfam; PF13774; Longin; 1.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..119
FT /note="Longin"
FT /evidence="ECO:0000259|PROSITE:PS50859"
SQ SEQUENCE 303 AA; 34469 MW; FC619C09CD7F110C CRC64;
MSMIFFACVV RVRDGLPLSA STDFYHTQDF LEWRRRLKSL ALRLAQYPGR GSAEGRDFSI
HFSSFGDVAC MAICSCQCPA TMAFCFLETL WWEFTASYDT TCIGLASRPY AFLEFDNIIQ
KVKWHFNYVS SSQMESSLEK IQEELKLQPP VVLTLEDTDV ANGVMNGHTP MHLEPAPNFR
MEPVTALGIL SLILNIMCAA LNLIRGVHLA EHSLQVAHEE IGNVLAFLVP FVACIFQCYL
YLFYSPARTM KVVLMLLFIC LGNMYLHGLR NLWQILFHIG VAFLSSYQIL TRQLQEKQSD
YGV
//
