ID   A0A2K5IVN1_COLAP        Unreviewed;       403 AA.
AC   A0A2K5IVN1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000020743.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000020743.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5IVN1; -.
DR   Ensembl; ENSCANT00000043715.1; ENSCANP00000020743.1; ENSCANG00000033797.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd04381; RhoGap_RalBP1; 1.
DR   Gene3D; 1.20.58.90; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR039767; RALBP1.
DR   InterPro; IPR049041; RalBP1-like_Ral-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR12783; RALA BINDING PROTEIN 1 RALBP1; 1.
DR   PANTHER; PTHR12783:SF5; RALA-BINDING PROTEIN 1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF20924; RLIP76_Ral-bd; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          1..179
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          348..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..403
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   403 AA;  47035 MW;  A1DF745A5AD9AB79 CRC64;
     MMYDGVRLPA VFRECIDYVE KYGMKCEGIY RVSGIKSKVD ELKAAYDREE STNLEEYEPN
     TVASLLKQYL RDLPENLLTK ELMPRFEEAC GRTTETEKVQ EFQRLLKELP ECNYLLISWL
     IVHMDHVIAK ELETKMNIQN ISIVLSPTVQ ISNRVLYVFF THVQELFGNV VLKQVTKPLR
     WSNMATMPTL PETQAGIKEE IRRQEFLLNC LHRDLQGGIK DLSKEERLWE VQRILTALKR
     KLREAKRQEC ETKIAQEIAS LSKEDVSKEE MNENEEVINI LLAQENEILT EQEELLAMEQ
     FLRRQIASEK EEIERLRNNH LNQAIHEERE AIIELRVQLR LLQMQRAKAE QQAQEDQEPE
     WRGGAVQPPR DGVLEPKAAK EQPKAGKEPA KPSPSRDRKE TSI
//