ID   A0A2K5IWS6_COLAP        Unreviewed;       275 AA.
AC   A0A2K5IWS6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=CYRIA/CYRIB Rac1 binding domain-containing protein {ECO:0000259|Pfam:PF07159};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000020956.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000020956.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Synapse, synaptosome
CC       {ECO:0000256|ARBA:ARBA00034102}.
CC   -!- SIMILARITY: Belongs to the CYFIP family.
CC       {ECO:0000256|ARBA:ARBA00025790}.
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DR   AlphaFoldDB; A0A2K5IWS6; -.
DR   Ensembl; ENSCANT00000043929.1; ENSCANP00000020956.1; ENSCANG00000033582.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR   InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR   InterPro; IPR008081; Cytoplasmic_FMR1-int.
DR   PANTHER; PTHR12195:SF4; CYTOPLASMIC FMR1-INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR12195; CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED; 1.
DR   Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
DR   PIRSF; PIRSF008153; FMR1_interacting; 1.
DR   PRINTS; PR01698; CYTOFMRPINTP.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080}.
FT   DOMAIN          64..245
FT                   /note="CYRIA/CYRIB Rac1 binding"
FT                   /evidence="ECO:0000259|Pfam:PF07159"
SQ   SEQUENCE   275 AA;  31851 MW;  2F5BF02969E24A81 CRC64;
     MAAQVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSLLYQP NFNTNFEDRN AFVTGIARYI
     EQATVHSSMN EMLEEGQEYA VMLYTWRSCS RQPNRVEIYE KTVEVLEPEV TKLMNFMYFQ
     RNAIERFCGE VRRLCHAERR KDFVSEAYLI TLGKFINMFA VLDELKNMKC SVKNDHSAYK
     RAAQFLRKMA DPQSIQESQN LSMFLANHNK ITQSLQQQLE VISGYEELLA DIVNLCVDYY
     ENRMYLTPSE KHMLLKVRVW GRQPVALRAL GGTQG
//