ID   A0A2K5IXK7_COLAP        Unreviewed;       104 AA.
AC   A0A2K5IXK7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Transmembrane protein 14C {ECO:0000256|ARBA:ARBA00039421};
OS   Colobus angolensis palliatus (Peters' Angolan colobus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=336983 {ECO:0000313|Ensembl:ENSCANP00000021290.1, ECO:0000313|Proteomes:UP000233080};
RN   [1] {ECO:0000313|Ensembl:ENSCANP00000021290.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Required for normal heme biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00037428}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC       {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004225}.
CC   -!- SIMILARITY: Belongs to the TMEM14 family.
CC       {ECO:0000256|ARBA:ARBA00007590}.
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DR   AlphaFoldDB; A0A2K5IXK7; -.
DR   Ensembl; ENSCANT00000044264.1; ENSCANP00000021290.1; ENSCANG00000034079.1.
DR   Proteomes; UP000233080; Unplaced.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.1740; Transmembrane protein 14-like; 1.
DR   InterPro; IPR005349; TMEM14.
DR   InterPro; IPR044890; TMEM14_sf.
DR   PANTHER; PTHR12668; TRANSMEMBRANE PROTEIN 14, 15; 1.
DR   PANTHER; PTHR12668:SF4; TRANSMEMBRANE PROTEIN 14C-RELATED; 1.
DR   Pfam; PF03647; Tmemb_14; 1.
PE   3: Inferred from homology;
KW   Heme biosynthesis {ECO:0000256|ARBA:ARBA00023133};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233080};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        30..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   104 AA;  10732 MW;  292A33E8B09A764E CRC64;
     VPLHWFGFGY AALVASGGIT GYVKARSVPS LAAGLLFGSL AGLGAYQLSQ DPRNVWVFLA
     TSGTLAGIMG KRFYHSGKFM PAGLIAGAIL LMAAKVGVST TDRL
//